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Methyl 4'-bromomethyl Biphenyl-2-carboxylate, identified by CAS number 114772-38-2, is a chemical compound of significant interest in organic synthesis and the pharmaceutical industry. Its utility as a building block stems from its specific chemical properties, making it a valuable reagent for R&D scientists and product formulators. Understanding these characteristics is key to leveraging its potential effectively.
Physically, Methyl 4'-bromomethyl Biphenyl-2-carboxylate typically presents as an off-white solid. Its melting point is generally reported around 56°C, indicating its stability as a solid under standard laboratory conditions. The compound's molecular formula is C15H13BrO2, with a molecular weight of 305.17 g/mol. The presence of a bromomethyl group (-CH2Br) makes it an excellent alkylating agent, capable of introducing the biphenyl carboxylate moiety into various molecular structures. This reactivity is crucial for its applications in complex organic syntheses.
The primary application for this compound lies in its role as a pharmaceutical intermediate. It is extensively used in the preparation of Active Pharmaceutical Ingredients (APIs). Most notably, it is a key intermediate in the synthesis of Telmisartan, a widely prescribed medication for hypertension. The ability to reliably buy this compound from experienced manufacturers in China ensures that pharmaceutical companies can maintain a steady supply for their production needs.
Beyond Telmisartan synthesis, Methyl 4'-bromomethyl Biphenyl-2-carboxylate finds application in general organic synthesis as a versatile building block. Its reactive bromomethyl group can participate in nucleophilic substitution reactions, enabling the formation of new carbon-carbon or carbon-heteroatom bonds. This makes it valuable for researchers developing new chemical entities or optimizing synthetic routes for various fine chemicals. For procurement managers, understanding the price and availability from reputable suppliers is essential for project planning and cost management.
In summary, Methyl 4'-bromomethyl Biphenyl-2-carboxylate is a crucial chemical intermediate with well-defined properties and significant applications, particularly in pharmaceutical synthesis. Its role as a key component for Telmisartan production highlights its importance, and sourcing it from reliable manufacturers and suppliers ensures quality and efficiency in research and production.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
