Pentafluorophenyl Chlorothionoformate (CAS 135192-53-9) is a fascinating molecule whose chemical properties dictate its broad utility in advanced synthesis. As a specialized supplier and manufacturer, we understand the importance of detailing these characteristics to our B2B clients, including R&D scientists and product formulators. This article explores its key properties and the applications that make it indispensable in modern chemistry.

The molecular formula C7ClF5OS and a molecular weight of approximately 262.58 g/mol characterize this compound. Its physical form is typically a clear liquid, with a density around 1.64 g/mL at 25°C and a refractive index (n20/D) of 1.48. These physical parameters are crucial for handling and formulation, especially for applications requiring precise measurements. The presence of the pentafluorophenyl group is central to its reactivity, offering a highly electron-withdrawing aromatic system that influences reaction pathways.

Chemically, the chlorothionoformate group (-OC(=S)Cl) is a highly reactive functional group. It readily participates in nucleophilic substitution reactions, making it an excellent electrophile for forming thioester bonds. This reactivity is foundational to its use as a derivatizing agent and a key intermediate in organic synthesis. Researchers often purchase Pentafluorophenyl Chlorothionoformate for its ability to efficiently attach the pentafluorophenylthioester moiety to various substrates.

The applications of Pentafluorophenyl Chlorothionoformate are diverse and impactful. In pharmaceutical development, its role in synthesizing fluorinated analogs is critical for optimizing drug efficacy and pharmacokinetic profiles. Its utility extends to agrochemical synthesis, where it can impart enhanced stability and biological activity to crop protection agents. For those in materials science, it serves as a functionalizing agent, improving the properties of polymers and coatings through enhanced chemical resistance and thermal stability.

Furthermore, its use in analytical chemistry as a derivatizing agent can significantly improve the detection limits and specificity of chromatographic techniques. Environmental scientists may also utilize it in the study of fluorinated compounds.

As a dedicated chemical supplier, we provide Pentafluorophenyl Chlorothionoformate with a guaranteed purity of ≥95% (GC), ensuring consistent performance in your sensitive reactions. We encourage potential buyers to inquire about our product specifications and to request samples for evaluation. Our commitment as a manufacturer in China is to support your scientific and industrial endeavors with high-quality chemical solutions. Buy with confidence from a supplier that understands your needs.