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For scientists and researchers in organic synthesis and medicinal chemistry, a thorough understanding of chemical properties is essential for successful experimental design and product development. Fmoc-D-Aph(Cbm)-OH, a derivative of D-phenylalanine, is one such compound whose chemical characteristics make it highly valuable. This Fmoc-protected amino acid derivative, known also by its systematic name (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-ureidophenyl)propanoic acid, features a unique combination of functional groups that dictate its reactivity and application. For professionals looking to buy Fmoc-D-Aph(Cbm)-OH, understanding these properties ensures optimal utilization in their projects.
The core structure of Fmoc-D-Aph(Cbm)-OH includes the standard Fmoc protecting group on the alpha-amino nitrogen, the carboxylic acid moiety, and the phenyl side chain modified with a carbamoylamino group. The Fmoc group is known for its sensitivity to basic conditions, allowing for its selective removal without affecting other protecting groups or the peptide backbone, a cornerstone of the Fmoc SPPS strategy. The carbamoylamino group on the phenyl ring can influence the electronic properties of the side chain and may participate in or modulate hydrogen bonding interactions within a peptide sequence. This nuanced reactivity is what makes it a sought-after building block.
When chemists and researchers seek to incorporate this compound into their syntheses, they rely on detailed technical specifications provided by a reputable Fmoc-D-Aph(Cbm)-OH supplier. These specifications typically include purity, molecular weight (445.47 g/mol), and sometimes data on solubility and stability. The melting point, often cited around 163.00 °C, provides an indication of its solid-state properties. Ensuring a consistent supply of Fmoc-D-Aph(Cbm)-OH with high purity is crucial, as impurities can lead to unwanted side products, complicating purification and potentially compromising the efficacy of the synthesized peptides.
For those operating in pharmaceutical research or advanced chemical synthesis, the quest for reliable sourcing is continuous. Identifying an experienced Fmoc-D-Aph(Cbm)-OH manufacturer in China or elsewhere can ensure access to well-characterized material at competitive Fmoc-D-Aph(Cbm)-OH prices. Ultimately, a deep appreciation for the chemical properties of Fmoc-D-Aph(Cbm)-OH, coupled with a commitment to sourcing from trusted suppliers, empowers researchers to push the boundaries of peptide chemistry and drug discovery.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
