For scientists and procurement professionals working with chemical intermediates, a thorough understanding of their physical and chemical properties, along with appropriate handling procedures, is fundamental. 4-Chloro-3-pyridinesulfonamide (CAS 33263-43-3) is a key intermediate in organic synthesis, particularly valued for its role in creating pharmacologically active compounds. As a leading manufacturer and supplier in China, we provide comprehensive information to ensure safe and effective use of this compound.

4-Chloro-3-pyridinesulfonamide typically presents as a pale yellow to yellow solid. Its melting point is generally reported in the range of 150-155°C, with some sources indicating decomposition at this temperature. This solid form requires careful handling to prevent dust formation and ensure accurate weighing for reactions. The chemical formula is C5H5ClN2O2S, and its molecular weight is approximately 192.62 g/mol. The molecule features a pyridine ring, a chlorine substituent at the 4-position, and a sulfonamide group (-SO2NH2) at the 3-position. This arrangement makes it reactive in various organic transformations, such as nucleophilic substitutions at the C4 position or modifications of the sulfonamide group.

Solubility data indicates that 4-Chloro-3-pyridinesulfonamide is slightly soluble in solvents like DMSO and methanol. For optimal reaction conditions, it's advisable to consult specific literature or experiment with appropriate solvent systems. Its stability is generally good under recommended storage conditions, which typically involve keeping it in a cool, dry place, often under inert gas (like nitrogen or argon) at 2-8°C, as advised by many chemical suppliers. Proper storage is crucial to maintain its high purity, often exceeding 97.0%, which is vital for sensitive synthetic processes.

Safety is a paramount concern when handling any chemical. 4-Chloro-3-pyridinesulfonamide is classified with hazard statements indicating it may be toxic if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation. Therefore, appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats should always be worn. Handling should be performed in a well-ventilated area, preferably a fume hood, to minimize inhalation exposure. When you buy this product, ensure you review the Safety Data Sheet (SDS) provided by the manufacturer for detailed safety protocols and first-aid measures.

For procurement managers and research scientists looking to purchase 4-Chloro-3-pyridinesulfonamide, choosing a reliable supplier in China is key. Factors such as batch consistency, purity verification, and adherence to safety standards are critical. We, as a prominent manufacturer, provide thorough documentation and support to ensure you receive a product that meets your exacting standards. Understanding the price relative to quality is also important; our competitive pricing reflects our efficient manufacturing processes and commitment to delivering value.

In conclusion, understanding the chemical properties and safety aspects of 4-Chloro-3-pyridinesulfonamide (CAS 33263-43-3) is essential for its effective application in synthesis. We are committed to being your trusted source for this intermediate, offering high purity and comprehensive support. Contact us to learn more about product specifications, pricing, and to place your order.