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The Chemical Properties and Handling of Methyl 3-amino-4-hydroxybenzoate

Understanding the fundamental chemical properties and proper handling procedures for compounds like Methyl 3-amino-4-hydroxybenzoate (CAS 536-25-4) is critical for anyone involved in its use, whether in a research laboratory or a manufacturing facility. This knowledge ensures safety, maintains product integrity, and optimizes its application in synthesis.

Methyl 3-amino-4-hydroxybenzoate, with the molecular formula C8H9NO3 and a molecular weight of approximately 167.16 g/mol, is an organic compound classified as an amino-substituted phenol. Its structure features a benzene ring substituted with a carboxylate methyl ester group, an amino group, and a hydroxyl group. These functional groups contribute to its reactivity and make it a valuable intermediate in organic synthesis. The reported melting point of 141-143°C and boiling point of around 295.73°C (estimated) provide key physical parameters for its identification and handling.

In terms of appearance, Methyl 3-amino-4-hydroxybenzoate is typically described as a white to light yellow powder. Its purity, often specified at 98% or higher, is a critical factor for its intended applications, especially in sensitive processes such as pharmaceutical synthesis or advanced research. When you buy Methyl 3-amino-4-hydroxybenzoate, it’s important to confirm the purity and request a Certificate of Analysis (CoA) from your supplier.

Safety information for Methyl 3-amino-4-hydroxybenzoate often highlights it as an irritant. Hazard codes such as Xi (Irritant) and Xn (Harmful if swallowed) are common. Precautionary statements typically advise avoiding inhalation of dust, preventing contact with skin and eyes, and using appropriate personal protective equipment (PPE), including gloves, eye protection, and respiratory protection if dust is generated. Proper ventilation in the workspace is also recommended. Always consult the Safety Data Sheet (SDS) provided by the manufacturer for comprehensive safety guidelines.

Proper storage is also essential for maintaining the quality of Methyl 3-amino-4-hydroxybenzoate. It is generally recommended to store the compound in a cool, dry place, away from direct sunlight and incompatible materials. Some suppliers may recommend storage under an inert atmosphere or at specific temperature ranges to prevent degradation. When sourcing this chemical, inquire about the recommended storage conditions to ensure its longevity and efficacy.

For those looking to purchase this compound, working with reputable chemical distributors or manufacturers ensures you receive a product that meets its stated specifications. Understanding these chemical properties and safety protocols is fundamental for effectively and safely utilizing Methyl 3-amino-4-hydroxybenzoate in your laboratory or production processes. Choosing a reliable manufacturer and adhering to safety guidelines will pave the way for successful outcomes.

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