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Understanding the Chemical Properties of (4S,5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic Acid

For scientists and procurement professionals in the chemical and pharmaceutical industries, a deep understanding of a compound's properties is fundamental to its successful application. (4S,5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid, identified by CAS number 949023-16-9, is a complex organic molecule that plays a critical role as an intermediate in the synthesis of Paclitaxel, a widely used anticancer drug.

Let's examine its key chemical attributes. The molecular formula, C24H21NO5, and a molecular weight of approximately 403.43 g/mol, provide the basic composition. What makes this compound particularly valuable are its stereochemical features and functional groups. The designation '(4S,5R)' indicates specific chiral centers, which are crucial for biological activity and stereoselective synthesis. This precise arrangement is essential for its function as a building block in the complex structure of Paclitaxel.

The molecule features several important functional groups: a benzoyl group, a methoxyphenyl moiety, a phenyl ring, and the core oxazolidine ring structure which contains both nitrogen and oxygen. The presence of a carboxylic acid group (-COOH) offers a reactive site for further chemical modifications, such as esterification or amide formation, which are common steps in pharmaceutical synthesis. The methoxyphenyl group can influence solubility and electronic properties, while the phenyl ring contributes to the overall molecular rigidity and interactions.

Physically, this compound is typically described as a white to off-white powder, with a high purity of ≥99.0%. Its stability under appropriate storage conditions is also a key consideration for manufacturers and users. Information regarding its solubility in various organic solvents is vital for reaction design and purification processes. When searching for this compound, using its full chemical name or CAS number alongside terms like 'chemical properties' or 'technical data sheet' will yield relevant information from chemical suppliers.

Understanding these chemical properties is not just an academic exercise; it directly impacts how efficiently and effectively this intermediate can be used in the synthesis of Paclitaxel and other potential pharmaceutical agents. Manufacturers who provide detailed specifications and product data sheets empower their clients to utilize these compounds with confidence, ensuring successful outcomes in research and production. For reliable sourcing, consider suppliers who highlight their commitment to chemical accuracy and product transparency.

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