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Chemical Properties and Pharmaceutical Applications of 2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide

In the realm of pharmaceutical manufacturing, understanding the precise chemical properties of intermediates is fundamental to successful drug synthesis. 2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide, identified by CAS 133627-46-0, is a prime example of such a critical compound. As a key intermediate for Nevirapine, its characteristics directly impact the efficiency and outcome of antiviral drug production. NINGBO INNO PHARMCHEM CO., LTD., a prominent manufacturer in China, offers this vital chemical with a focus on quality and consistency.

The compound typically presents as a pale yellow solid, a physical characteristic that aids in its identification and handling. Its melting point, recorded between 189-191°C, indicates a stable solid form under standard conditions. The molecular formula, C12H9Cl2N3O, highlights its complex organic structure, which is designed for specific reactivity in synthetic pathways. Further chemical properties, such as solubility in common organic solvents like chloroform and dichloromethane, are crucial for its use in various reaction conditions. This makes it a versatile component in chemical synthesis processes.

The primary application of 2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide is as an intermediate in the synthesis of Nevirapine. Nevirapine is a widely used non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infection. The demand for such antiviral drugs underscores the importance of a reliable supply of high-purity intermediates. NINGBO INNO PHARMCHEM CO., LTD. ensures that its product meets the rigorous standards required by the pharmaceutical industry, contributing to the global fight against HIV.

Beyond its direct role in Nevirapine production, this chemical intermediate also finds utility in broader pharmaceutical research and development. Its pyridine derivative structure makes it a valuable component for scientists exploring new molecular entities or optimizing existing synthetic routes. By providing this compound, NINGBO INNO PHARMCHEM CO., LTD. supports innovation within the pharmaceutical sector. For businesses looking to buy this essential chemical, partnering with a reputable Chinese supplier like NINGBO INNO PHARMCHEM CO., LTD. guarantees access to materials that meet exacting specifications, thereby ensuring the quality and efficacy of the final pharmaceutical products.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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