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The Chemical Properties and Specifications of 2-Bromo-5-methyl-3-nitropyridine

For chemists and material scientists, a deep understanding of a chemical's properties is fundamental to its successful application. 2-Bromo-5-methyl-3-nitropyridine, identified by its CAS number 23056-46-4, is a specialized organic compound whose detailed specifications are crucial for its effective use as a synthetic intermediate. This article delves into its key physical and chemical characteristics, providing essential information for procurement and research professionals.

The molecular formula of 2-Bromo-5-methyl-3-nitropyridine is C6H5BrN2O2, with a molecular weight of approximately 217.02 g/mol. Its density is reported as 1.709 g/cm³, indicating a relatively dense solid. Key thermophysical properties include a boiling point of 276.7°C and a flash point of 121.1°C, which are important considerations for handling and storage safety protocols. The refractive index is noted as 1.599.

From a specification standpoint, a critical parameter for buyers is its assay, which typically needs to be ≥98.0% for most demanding organic synthesis applications. Moisture content is also closely monitored, with a recommended limit of ≤0.5% to ensure stability and reactivity. The compound's appearance is consistently described as a yellow to brown crystalline powder, a visual characteristic that aids in preliminary identification and quality assessment.

The significance of these properties lies in their direct impact on its utility as an intermediate. The bromine atom provides a site for nucleophilic substitution or participation in cross-coupling reactions, while the nitro group exerts an electron-withdrawing effect, influencing the reactivity of the pyridine ring and other substituents. The methyl group adds steric and electronic character. This combination of features makes 2-Bromo-5-methyl-3-nitropyridine a versatile precursor in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals.

For businesses looking to purchase this compound, understanding these specifications is paramount. Working with a trusted manufacturer or supplier that adheres to these quality standards ensures that the material procured will perform as expected in complex synthetic processes. The availability of such well-characterized intermediates from reliable sources, particularly from manufacturers in China, significantly streamlines research and development efforts and large-scale production planning. When you seek this chemical, always inquire about its detailed specifications to ensure it meets your project's stringent requirements.

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