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2,3-Difluoro-6-Nitroaniline (CAS 153505-39-6) is a compound of considerable interest in organic chemistry due to its unique structural features and resultant chemical properties. As a fluorinated aromatic amine with a nitro substituent, it offers a rich reactivity profile that makes it a valuable intermediate in various synthesis applications, particularly within the pharmaceutical and fine chemical sectors.
The molecule's core is a benzene ring, substituted with an amino group (-NH2), two fluorine atoms (-F) at the 2 and 3 positions, and a nitro group (-NO2) at the 6 position. The electronegative fluorine atoms exert a significant inductive effect, influencing the electron density of the aromatic ring and the basicity of the amino group. This electronic perturbation can enhance or modify the compound's reactivity in electrophilic and nucleophilic substitution reactions. The nitro group, a strong electron-withdrawing group, further influences the ring's reactivity and also serves as a functional handle that can be readily transformed, most commonly through reduction to an amino group.
In synthesis, 2,3-Difluoro-6-Nitroaniline is frequently employed as a key building block. Its utility spans the creation of complex heterocyclic compounds, novel pharmaceutical agents, and advanced materials. For instance, the amino and nitro functionalities can be manipulated to construct fused ring systems or to attach diverse side chains, leading to molecules with tailored biological activities or physical properties.
The demand for such versatile intermediates underscores the importance of reliable suppliers. Manufacturers and researchers seeking to buy high-quality 2,3-Difluoro-6-Nitroaniline, typically with a purity of 95%min, can find a dependable source in China. NINGBO INNO PHARMCHEM, a leading manufacturer and supplier, is committed to providing this essential chemical with consistent quality and competitive pricing. We encourage potential clients to contact us for a quote and to learn more about how our 2,3-Difluoro-6-Nitroaniline can support your innovative chemical synthesis projects.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
