Understanding the fundamental chemical properties of an intermediate is crucial for chemists aiming to design efficient synthetic routes. 3-Bromo-4-Chloro-Benzaldehyde, bearing the CAS number 86265-88-5, is a significant player in organic synthesis due to its well-defined characteristics and reactivity. As a leading manufacturer in China, we are committed to providing detailed insights into this compound, enabling researchers and formulators to leverage its full potential. This article explores its key properties and diverse applications, underscoring its value as a pharmaceutical intermediate and a versatile organic building block.

The chemical profile of 3-Bromo-4-Chloro-Benzaldehyde is defined by its molecular formula C7H4BrClO and a molecular weight of 219.46. It typically presents as a white powder, with a reported melting point of 70°C. This solid form simplifies handling and storage, especially for laboratory use. Its boiling point is approximately 277.8±20.0°C at 760 Torr, and it has a density of 1.698±0.06 g/cm³. The presence of both a bromo and a chloro substituent on the aromatic ring, adjacent to the aldehyde group, imparts unique electronic and steric properties. These features make it a highly versatile substrate for a wide array of organic transformations, including nucleophilic aromatic substitution, electrophilic aromatic substitution (though often deactivated by the halogens), and various metal-catalyzed cross-coupling reactions.

The synthetic utility of 3-Bromo-4-Chloro-Benzaldehyde is vast, particularly in the development of pharmaceuticals and fine chemicals. The aldehyde functional group is readily converted into other functional groups, such as alcohols (via reduction), carboxylic acids (via oxidation), or can participate in condensation reactions to form imines, oximes, and hydrazones. The halogen atoms, especially the bromine, are excellent leaving groups in palladium-catalyzed cross-coupling reactions like Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions are cornerstones of modern organic synthesis, allowing for the precise construction of complex carbon frameworks. For example, it can be used to synthesize substituted benzaldehydes or aromatic acids with specific substitution patterns, which are common motifs in drug discovery. When seeking to buy this compound, knowledge of these reaction pathways is key.

As a reliable manufacturer and supplier of 3-Bromo-4-Chloro-Benzaldehyde (CAS 86265-88-5) from China, we ensure a purity of 97%, making it suitable for the most demanding applications. Whether your project involves laboratory research, process development, or industrial-scale chemical production, our supply chain is designed for consistency and efficiency. We understand the importance of reliable access to high-quality intermediates for the pharmaceutical sector, where the correct stereochemistry and purity are paramount. Furthermore, our competitive pricing makes it an attractive option for companies looking to optimize their synthesis costs.

In conclusion, 3-Bromo-4-Chloro-Benzaldehyde is more than just a chemical compound; it's a gateway to complex molecular architectures. Its distinct chemical properties and broad synthesis applications make it an indispensable intermediate for chemists. We encourage researchers and formulators to consider us as their trusted supplier from China, offering not only a high-quality product but also the expertise and reliability necessary for successful chemical synthesis projects. Contact us to explore how we can support your next innovation.