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The Chemical Properties and Synthesis of Menadione (Vitamin K3)

Menadione, also known as Vitamin K3, identified by CAS number 58-27-5, is a synthetic naphthoquinone derivative that holds significant importance in various industries, particularly pharmaceuticals and animal nutrition. Understanding its chemical properties and synthesis pathways is crucial for manufacturers and researchers alike. As a leading chemical manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers high-purity Menadione and insights into its production. This article explores the chemical characteristics and common synthesis routes of Menadione.

Chemically, Menadione is classified as 2-methyl-1,4-naphthoquinone. Its structure dictates its reactivity and applications. It typically appears as light yellow crystalline powder, with a molecular weight of 172.18. Key physical properties include a melting point of 104-107°C and a boiling point around 304.50°C at standard pressure. Menadione exhibits a degree of solubility in water and ethanol but is insoluble in non-polar solvents like ether and benzene. Its sensitivity to light, leading to color degradation, is an important consideration for handling and storage. These distinct chemical properties make it a valuable compound for specific industrial processes.

The synthesis of Menadione typically involves the oxidation of 2-methylnaphthalene. A common industrial method employs chromic anhydride in glacial acetic acid, followed by purification steps. The process involves carefully controlled oxidation at specific temperatures to yield Menadione. Alternative synthesis routes may utilize hydrogen peroxide or other oxidizing agents under catalytic conditions. The efficiency and purity achieved in these synthesis pathways are critical for producing Menadione that meets the stringent quality requirements of the pharmaceutical and animal feed industries. As a manufacturer, we continuously optimize these processes to ensure high purity (99.5%min) and cost-effectiveness.

The successful synthesis and purification of Menadione are vital for its downstream applications. In pharmaceuticals, its role as a hemostatic agent relies on its ability to facilitate blood clotting factor synthesis. In animal feed, it contributes to the overall health and growth of livestock. Businesses looking to purchase Menadione can benefit from understanding these chemical aspects and the manufacturing rigor involved. By sourcing from a reliable supplier like us, you ensure access to a product that has undergone rigorous quality control from raw material to finished compound.

In conclusion, Menadione (Vitamin K3) is a chemically distinct compound with critical applications. Its synthesis from 2-methylnaphthalene and its specific chemical properties define its utility. NINGBO INNO PHARMCHEM CO.,LTD., as a leading Menadione manufacturer and supplier in China, is committed to providing high-quality product with reliable Menadione prices. We invite you to contact us to learn more about our chemical expertise and to procure Menadione for your business needs.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
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