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The Chemical Properties and Synthesis of (R)-Dihydro-4-propyl-2(3H)-furanone

Understanding the fundamental chemical properties and synthesis routes of key pharmaceutical intermediates is essential for R&D scientists and process chemists. (R)-Dihydro-4-propyl-2(3H)-furanone, identified by CAS number 63095-51-2, is a compound of significant interest due to its critical role in the synthesis of Brivaracetam. As a leading manufacturer in this space, we aim to provide insights into this versatile molecule.

Chemically, (R)-Dihydro-4-propyl-2(3H)-furanone is a chiral lactone. Its molecular formula is C7H12O2, with a molecular weight of approximately 128.17 g/mol. While specific physical properties like melting and boiling points can vary slightly based on purity and measurement conditions, it is typically described as a colorless oil. Its solubility in common organic solvents such as chloroform, ethanol, and methanol is generally moderate, making it amenable to various reaction conditions and purification techniques employed in pharmaceutical synthesis.

The stereochemistry of this molecule is particularly important. The '(R)' designation in its name indicates a specific spatial arrangement of atoms at a chiral center, which is crucial for its function as a chiral building block in the synthesis of Brivaracetam. This specific enantiomer is required to achieve the desired pharmacological activity of the final drug product. Maintaining this stereochemical integrity throughout the synthesis process is a key focus for us as a manufacturer.

Several synthetic pathways can lead to (R)-Dihydro-4-propyl-2(3H)-furanone. While detailed proprietary synthesis routes are confidential, general approaches often involve the stereoselective reduction or cyclization of precursor molecules. For instance, routes might stem from chiral starting materials or employ asymmetric synthesis techniques to establish the required (R)-configuration. The efficiency, cost-effectiveness, and scalability of these synthesis methods are critical considerations for industrial production. Our manufacturing processes are optimized to ensure high yields and purity, typically achieving 99% for this key intermediate.

For R&D scientists looking to buy (R)-Dihydro-4-propyl-2(3H)-furanone, understanding these chemical characteristics is vital for designing effective reaction schemes. As a supplier, we ensure that our product is consistently manufactured to precise specifications, supporting your research and development efforts. Whether you are exploring novel applications or scaling up Brivaracetam production, our high-purity intermediate provides a reliable foundation.

In summary, (R)-Dihydro-4-propyl-2(3H)-furanone (CAS 63095-51-2) is more than just a chemical structure; it embodies precise stereochemistry and valuable reactivity. Its properties make it an indispensable intermediate in pharmaceutical synthesis. As a dedicated manufacturer and supplier, we are committed to providing this high-quality compound to meet the demands of the global pharmaceutical industry. Contact us to learn more about our manufacturing capabilities and to secure your supply.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

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  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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