Isonicotinic acid, scientifically known as 4-Pyridinecarboxylic acid, is a compound that merits close attention within the chemical and pharmaceutical sectors. With the CAS number 55-22-1 and the molecular formula C6H5NO2, this organic acid boasts a molecular weight of 123.10900. Its physical characteristics, described as a white or light brown crystal or crystalline powder, are complemented by a density of 1.293 g/cm³ and a high boiling point of 260 °C at 15 mmHg. These attributes contribute to its stability and utility in various chemical processes.

The specifications for isonicotinic acid highlight its suitability for demanding applications. A purity of ≥99% ensures that it serves effectively as an intermediate, minimizing unwanted side reactions and byproducts in pharmaceutical synthesis. Key parameters like a drying loss of ≤0.5%, residue of ≤0.1%, and a heavy metal content of ≤20ppm further attest to its high quality. These stringent standards are critical for manufacturers who prioritize the integrity of their final drug products. When looking for a supplier in China, verifying these specifications is paramount.

The primary value of isonicotinic acid lies in its role as a versatile intermediate. It is particularly recognized for its involvement in the synthesis of Fexofenadine, a widely used non-sedating antihistamine. The production of Fexofenadine hydrochloride, a common salt form, directly benefits from the purity of isonicotinic acid. Similarly, its application as a precursor for Isoniazid, a vital drug in the fight against tuberculosis, solidifies its importance in global health. For companies engaged in these synthesis pathways, the ability to purchase isonicotinic acid reliably is key.

Proper storage and packaging are also essential for maintaining the quality of isonicotinic acid. It should be stored in a cool, dry, well-closed container, protected from moisture and excessive heat or light. Typically supplied in 25kg cardboard drums or as per customer requirements, its handling demands adherence to standard chemical safety protocols. When considering sourcing this compound, inquire about their packaging and storage solutions to ensure product integrity.

In conclusion, the detailed chemical properties and rigorous specifications of isonicotinic acid make it an indispensable component for pharmaceutical manufacturers. Its critical role in synthesizing essential medicines like Fexofenadine and Isoniazid underscores the need for high-purity sourcing. Exploring options to buy from reputable Chinese manufacturers will provide the quality and reliability required for successful pharmaceutical production.