Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
The intricate world of chemical synthesis relies on specialized building blocks to construct complex molecules for various industries, notably pharmaceuticals. 2-Fluoro-5-formylbenzonitrile, identified by CAS number 218301-22-5, is one such vital intermediate, primarily recognized for its role in the synthesis of Olaparib, a groundbreaking PARP inhibitor. Understanding its chemical properties and where to source it is key for researchers and chemical manufacturers.
Chemically, 2-Fluoro-5-formylbenzonitrile is a benzonitrile derivative featuring both a nitrile group and a formyl (aldehyde) group, along with a fluorine atom. This combination of functional groups makes it highly reactive and versatile for various organic transformations. Its typical form is a white to pale yellow powder, with a purity of ≥98.0% often specified for pharmaceutical applications. The presence of the aldehyde group allows for nucleophilic additions, condensations, and reductions, while the nitrile group can undergo hydrolysis or reduction. These reactions are foundational in building the complex heterocyclic structures characteristic of many advanced pharmaceuticals.
When considering the synthesis applications of 2-Fluoro-5-formylbenzonitrile, its utility in constructing the core structure of Olaparib is most prominent. Beyond this, its reactive nature makes it a valuable intermediate for synthesizing other fine chemicals and potential drug candidates. Researchers often look for reliable suppliers who can provide consistent quality and accurate specifications to ensure predictable reaction outcomes. For procurement managers, identifying manufacturers, especially those in China, that offer competitive pricing for this crucial intermediate is a strategic advantage.
To effectively source 2-Fluoro-5-formylbenzonitrile, prospective buyers should prioritize suppliers who provide detailed product specifications, Certificates of Analysis (CoA), and robust safety data. Understanding packaging options and delivery capabilities is also important, particularly for large-scale synthesis projects. By partnering with knowledgeable and quality-focused chemical suppliers, organizations can ensure a stable supply of this essential building block, facilitating innovation in pharmaceutical and fine chemical synthesis.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
