The field of chemical synthesis is continually evolving, with the demand for specialized intermediates growing exponentially. BOC-Pyr-Oet, identified by CAS number 144978-12-1, stands out as a crucial pharmaceutical intermediate with significant applications in organic chemistry and drug development. Understanding its synthesis utility is key for chemists and researchers aiming to create advanced therapeutic molecules.

BOC-Pyr-Oet, also known by its IUPAC name Ethyl (S)-1-Boc-5-oxopyrrolidine-2-carboxylate, is a protected pyroglutamic acid derivative. Its molecular formula is C12H19NO5, and its molecular weight is approximately 257.28 g/mol. As a white solid with a melting point typically between 52.0-56.0 °C, it is a stable compound that can be readily used in various reaction conditions. The tert-butyloxycarbonyl (Boc) group serves as a protecting group, allowing for selective modifications elsewhere in the molecule during complex synthesis pathways.

The primary applications of BOC-Pyr-Oet are rooted in its role as a versatile building block in the synthesis of pharmacologically active compounds. It is widely employed in the creation of peptides and amides, which are fundamental components of many modern drugs. Notably, BOC-Pyr-Oet has been instrumental in the development of inhibitors targeting specific enzymes and biological pathways. For instance, it is a known intermediate in the synthesis of Hepatitis C virus (HCV) protease inhibitors, contributing to the treatment of this chronic liver disease. Additionally, its utility extends to the synthesis of alkyl renin inhibitors, which are crucial for managing hypertension and related cardiovascular conditions.

For research scientists and formulation chemists, sourcing high-quality BOC-Pyr-Oet is paramount. Reputable chemical manufacturers, particularly those in China, offer this intermediate with high purity levels, ensuring reproducible results in synthesis. When you look to buy BOC-Pyr-Oet, it's advisable to partner with suppliers who provide detailed product specifications and certificates of analysis. This ensures the material's integrity and suitability for your specific synthetic targets. Reliable manufacturers also offer competitive pricing and flexible order quantities, supporting both small-scale research and large-scale production.

In essence, BOC-Pyr-Oet is a pivotal intermediate that empowers chemists to construct sophisticated molecules essential for pharmaceutical innovation. Its specific chemical properties and broad applicability make it a valuable asset in the drug discovery pipeline. By securing a consistent supply from trusted manufacturers, researchers can accelerate their work and bring new therapies to market more efficiently.