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The intricate field of organic chemistry is built upon a foundation of key intermediates, each possessing unique properties that enable the creation of complex molecules. 2',4'-Dichloroacetophenone, with its CAS number 2234-16-4, is a prime example of such a compound. Its structure and reactivity make it an invaluable asset across multiple industries, particularly in pharmaceuticals and agrochemicals. For chemists and R&D professionals, understanding its synthesis and diverse applications is crucial for leveraging its full potential.
Chemical Profile: Structure and Properties
2',4'-Dichloroacetophenone, chemically known as 1-(2,4-dichlorophenyl)ethanone, is characterized by a phenyl ring substituted with chlorine atoms at the 2' and 4' positions, and an acetyl group. Its molecular formula is C8H6Cl2O, and its molecular weight is approximately 189.04 g/mol. Typically appearing as a white to pale crystalline solid, it possesses a melting point in the range of 29-34°C. Its solubility in common organic solvents like chloroform and methanol, while being sparingly soluble in water, dictates its handling and reaction conditions. As a dedicated manufacturer, ensuring these precise specifications is paramount for providing reliable materials.
Synthesis Pathways: From Raw Materials to Intermediate
The production of 2',4'-Dichloroacetophenone typically involves the Friedel-Crafts acylation of 1,3-dichlorobenzene. Common reagents used in this process include acetyl chloride or acetic anhydride, catalyzed by Lewis acids such as anhydrous aluminum chloride. The reaction is carefully controlled, often involving specific temperature ranges and reaction times, followed by purification steps like distillation or recrystallization to achieve the desired purity, often exceeding 99%. Understanding these production methods is key for anyone looking to buy 2',4'-Dichloroacetophenone, ensuring they are acquiring a product made through robust and validated processes.
Key Applications: Beyond the Basics
The utility of 2',4'-Dichloroacetophenone extends across several critical sectors:
As a leading supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to producing high-quality 2',4'-Dichloroacetophenone. We offer reliable sourcing solutions for businesses worldwide, providing detailed product specifications and competitive pricing. We encourage prospective clients to request a quote to explore how our expertise can support your synthesis needs.
In conclusion, 2',4'-Dichloroacetophenone is a fundamental intermediate whose chemistry enables significant advancements in pharmaceutical and agrochemical industries, as well as in the broader fine chemical landscape. Reliable sourcing from expert manufacturers is key to unlocking its full potential in your R&D and production processes.
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