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The Chemistry of 3,6-Diiodopyridazine: Synthesis, Properties, and Applications

Understanding the fundamental chemistry of key intermediates is vital for progress in scientific research and industrial development. 3,6-Diiodopyridazine (CAS 20698-04-8) is a compound that embodies this importance, offering a unique blend of structural characteristics and reactivity. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing this high-value chemical intermediate.

The synthesis of 3,6-Diiodopyridazine often begins with readily available pyridazine precursors. Through targeted chemical reactions, typically involving halogenation, the desired diiodo-substituted product is achieved. This process demands careful control of reaction conditions to ensure high yield and purity. The resulting compound is characterized by its chemical formula C4H2I2N2 and a molecular weight of 331.88 g/mol. Its physical appearance is typically a white to beige powder or crystalline solid, stable when stored appropriately, usually refrigerated between 2-8°C.

The true value of 3,6-Diiodopyridazine lies in its applications. Its utility as a reactant in the preparation of conjugated ethynyl and vinylpyridazines is paramount for material science, particularly for creating rod-like conjugated molecules with desirable light-emitting properties. These molecules are integral to the performance of organic light-emitting diodes (OLEDs), contributing to advancements in display and lighting technologies. The iodine atoms provide excellent handles for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions, allowing for the precise construction of pi-conjugated systems.

In addition to its role in materials science, 3,6-Diiodopyridazine serves as a crucial pharmaceutical raw intermediate. The pyridazine nucleus is a common feature in many biologically active molecules, and the presence of iodine atoms allows for regioselective functionalization, enabling medicinal chemists to synthesize diverse drug candidates efficiently. The demand for high-purity (often 97% min) 3,6-Diiodopyridazine is driven by the need for reliable and reproducible synthetic routes in drug discovery and development.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying top-tier 3,6-Diiodopyridazine. Our understanding of its synthesis, properties, and applications ensures that we provide a product that meets the rigorous standards of researchers and manufacturers. By offering this essential building block, we aim to facilitate breakthroughs in both advanced materials and life-saving pharmaceuticals.

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