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Understanding the fundamental chemistry of key intermediates is crucial for chemists and engineers in driving innovation across various industries. 3-Fluorobenzoic Acid (CAS 455-38-9), a white powder with a high purity assay (typically ≥98%), is a prime example of such a versatile compound. Its unique molecular structure and reactivity make it an indispensable building block, particularly in pharmaceutical synthesis, agrochemicals, and material science. As a dedicated manufacturer, we are pleased to share insights into its properties and synthesis.
The chemical identity of 3-Fluorobenzoic Acid is C7H5FO2, with a molecular weight of 140.11. The presence of a fluorine atom at the third carbon position on the benzene ring, ortho to the carboxyl group, significantly influences its chemical behavior. Fluorine, being highly electronegative, withdraws electron density from the aromatic ring, affecting its reactivity in electrophilic aromatic substitution reactions. It also influences the acidity of the carboxyl group. The melting point typically falls within the range of 122-129 °C, and it is soluble in water to some extent, with better solubility in organic solvents.
The synthesis of 3-Fluorobenzoic Acid can be achieved through various routes. One common method involves the oxidation of 3-fluorobenzaldehyde or related precursors. Another approach might include the Sandmeyer reaction or related diazotization chemistry starting from a suitably substituted aniline. For example, deaminating 2-amino-5-chlorobenzoic acid has also been cited as a pathway. As a manufacturer, we employ optimized synthetic pathways to ensure high yield and purity, delivering a consistent product that meets demanding specifications.
The chemical reactivity of 3-Fluorobenzoic Acid allows it to participate in a wide range of reactions, including esterification, amidation, and further functionalization of the aromatic ring. These reactions are fundamental to its role as an intermediate, enabling the creation of more complex molecules with specific desired properties.
For professionals seeking to buy 3-Fluorobenzoic Acid, understanding these chemical characteristics is key to its effective application. Whether you are involved in pharmaceutical development, designing new agrochemicals, or creating advanced materials, the reliable quality and predictable reactivity of 3-Fluorobenzoic Acid are essential. We are committed to being a premier supplier of this compound, ensuring our customers receive material that facilitates their research and production goals. Contact us to learn more about our manufacturing capabilities and to obtain a quote for your 3-Fluorobenzoic Acid requirements.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
