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NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing the scientific community with high-quality chemical reagents, and understanding the chemistry behind these compounds is key to their effective use. Fmoc-D-2-Fluorophenylalanine is a sophisticated building block whose synthesis and properties are of great interest to organic chemists and researchers in the pharmaceutical and biotech industries. This compound uniquely combines the well-established Fmoc (9-fluorenylmethyloxycarbonyl) protecting group with a D-phenylalanine core that has a fluorine atom substituted at the ortho position of its phenyl ring.
The synthesis of Fmoc-D-2-Fluorophenylalanine typically involves the N-acylation of D-2-fluorophenylalanine with a suitable Fmoc-introducing reagent, such as Fmoc-Cl or Fmoc-OSu. These reactions are carried out under controlled conditions to ensure high yield and purity, preserving the crucial stereochemistry of the D-amino acid. The Fmoc group itself is known for its base-lability, allowing for facile deprotection using mild bases like piperidine, which is a cornerstone of efficient Fmoc-based solid-phase peptide synthesis (SPPS). For those aiming to buy Fmoc-D-2-Fluorophenylalanine, our stringent quality control measures ensure that the product adheres to exact specifications for Fmoc-D-2-Fluorophenylalanine synthesis.
The incorporation of fluorine into the phenylalanine structure of Fmoc-D-2-Fluorophenylalanine imparts distinct chemical and physical properties. Fluorine's high electronegativity can influence the electronic distribution within the molecule, affecting reactivity and binding interactions. Furthermore, the C-F bond is strong, contributing to increased metabolic stability, a highly desirable trait in drug development. These characteristics make Fmoc-D-2-Fluorophenylalanine a valuable component in SAR studies, bioconjugation, and the development of peptide-based therapeutics, where fine-tuning molecular behavior is critical. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our Fmoc-D-2-Fluorophenylalanine is synthesized to the highest standards to support these advanced applications.
By offering Fmoc-D-2-Fluorophenylalanine, NINGBO INNO PHARMCHEM CO.,LTD. provides researchers with a versatile tool that bridges fundamental organic chemistry with cutting-edge pharmaceutical innovation. Understanding its synthesis and inherent properties allows scientists to confidently integrate it into their complex Fmoc-D-2-Fluorophenylalanine drug development programs. We are committed to advancing scientific discovery by supplying reliable, high-quality reagents like Fmoc-D-2-Fluorophenylalanine, empowering chemists to explore new molecular frontiers.
Manufacturing Facilities
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to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
