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The Chemistry Behind Rivaroxaban: Understanding the Role of 4-(4-Aminophenyl)morpholin-3-one

The development of novel pharmaceuticals often hinges on the availability of precisely engineered chemical intermediates. For the widely recognized anticoagulant, Rivaroxaban, a key player in its synthesis is 4-(4-Aminophenyl)morpholin-3-one, also known by its CAS number 438056-69-0. As a dedicated manufacturer and supplier of this compound, we aim to shed light on its chemical significance and its indispensable role in pharmaceutical innovation.

The synthesis of Rivaroxaban is a multi-step process, and 4-(4-Aminophenyl)morpholin-3-one forms a foundational element. Its molecular structure, characterized by the presence of an amine group on a phenyl ring attached to a morpholin-3-one core, provides the necessary reactive sites for further chemical transformations. This structure allows it to be incorporated efficiently into the complex molecular architecture of Rivaroxaban, contributing significantly to the drug's pharmacological activity as a direct factor Xa inhibitor.

For scientists engaged in drug discovery and development, sourcing high-quality intermediates is crucial. The requirement for an assay of ≥99.0% for 4-(4-Aminophenyl)morpholin-3-one is standard, ensuring that subsequent reactions proceed with high yield and minimal by-product formation. The physical properties, such as its appearance as a white to light yellow solid and low moisture content, are indicators of its stability and suitability for demanding pharmaceutical synthesis. When researchers seek to purchase this compound, they are looking for a partner who understands these critical quality attributes.

Our commitment as a manufacturer in China is to provide a consistent and reliable supply of 4-(4-Aminophenyl)morpholin-3-one to the global pharmaceutical market. We understand that the journey from laboratory synthesis to commercial production requires robust and scalable solutions. By offering competitive pricing and flexible packaging options, we support our clients at every stage of their drug development pipeline. If your research involves the synthesis of anticoagulants or other complex pharmaceuticals, exploring the benefits of procuring this vital intermediate from an established supplier is a strategic move.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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