N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt, more commonly known by its acronym BES sodium salt (CAS 66992-27-6), is a compound whose chemical characteristics underpin its widespread utility across scientific and industrial domains. From its fundamental role as a biochemical buffer to its emerging applications in advanced materials, understanding the chemistry of BES sodium salt is key to appreciating its value. As a dedicated chemical manufacturer, we provide insights into its properties and why it's a sought-after material.

Molecular Structure and Chemical Properties
BES sodium salt is a zwitterionic compound, meaning it possesses both positive and negative charges within the same molecule. Structurally, it is an ethanesulfonic acid derivative with a tertiary amine group substituted with two hydroxyethyl chains. Its molecular formula is C6H14NNaO5S, and its molecular weight is approximately 235.23 g/mol. The sulfonic acid group is deprotonated, forming a sulfonate anion, while the tertiary amine nitrogen is protonated at lower pH values, existing as a cation, thus forming a zwitterion. However, in its common salt form, it is the sodium salt of the sulfonate, with the amine nitrogen typically being neutral under physiological conditions or weakly basic.

Key chemical properties that make BES sodium salt valuable include:

• Buffering Capacity: With a pKa of around 7.1, it effectively buffers in the near-neutral pH range (6.4-7.8).
• Solubility: It is soluble in water, a critical property for its use in aqueous solutions and biological media.
• Stability: BES sodium salt exhibits good chemical stability under typical laboratory and physiological conditions.
• Low Metal Binding: Unlike some other buffers, it shows minimal affinity for metal ions, reducing interference in assays.
• Low Toxicity: Its low toxicity profile makes it suitable for applications involving biological systems and sensitive research.

These properties make it an attractive choice for researchers looking to buy BES sodium salt for a wide array of applications.

Diverse Industrial Applications
The chemical versatility of BES sodium salt translates into its use in several key industries:

• Biotechnology and Life Sciences: As a zwitterionic buffer, it is indispensable in enzyme assays, protein purification, electrophoresis, and as a component in cell culture media. Its ability to maintain stable pH is crucial for preserving the integrity and activity of biomolecules.
• Pharmaceutical Industry: It serves as a valuable excipient or intermediate in drug formulations. Its solubility-enhancing and pH-stabilizing properties can improve the efficacy and shelf-life of pharmaceutical products. Manufacturers looking for reliable pharmaceutical intermediates often specify BES sodium salt for its favorable characteristics.
• Diagnostic Assays: In the development of diagnostic kits and reagents, BES sodium salt is used to maintain optimal pH for enzyme-based reactions and to stabilize assay components, ensuring accurate and reproducible results.
• Cosmetics: Its mildness and pH-regulating capabilities make it suitable for use in certain cosmetic formulations, contributing to product stability and skin compatibility.

For businesses seeking to incorporate BES sodium salt into their products or processes, sourcing from a reputable manufacturer is essential. We, as a leading supplier of fine chemicals in China, ensure that our BES sodium salt meets stringent purity standards. By understanding its chemical underpinnings, industries can better leverage its capabilities. Requesting a quote from a trusted BES sodium salt supplier is the first step toward integrating this valuable compound into your operations.