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Mildronate, scientifically identified by CAS number 76144-81-5, is a chemical compound with a distinctive structure that underpins its significant pharmacological activity. As a pharmaceutical intermediate, understanding its chemical composition and how it functions is key to appreciating its therapeutic value. NINGBO INNO PHARMCHEM CO., LTD is a dedicated supplier of high-quality Mildronate, ensuring that scientific and medical communities have access to this vital compound.
The molecular formula of Mildronate is C6H14N2O2, and its structure is a structural analog of carnitine. This similarity is central to its mechanism of action. Mildronate effectively competes with gamma-butyrobetaine hydroxylase, an enzyme involved in carnitine biosynthesis. By inhibiting this enzyme, Mildronate curbs the body's production of carnitine. This action directly impacts the transport of long-chain fatty acids into the mitochondria, thereby influencing cellular energy metabolism. The ability to inhibit carnitine biosynthesis is a hallmark of its therapeutic effect.
The functional consequence of this inhibition is a shift in cellular energy production. Under conditions of stress or low oxygen (ischemia), where fatty acid oxidation becomes less efficient, Mildronate promotes the utilization of glucose for energy. This metabolic flexibility is crucial for maintaining cellular integrity and function in oxygen-deprived tissues, particularly in the heart and brain. Its impact on myocardial energy metabolism and its role as a neuroprotective agent are direct results of this biochemical process.
Mildronate's applications span from treating cardiovascular diseases like angina and heart failure to supporting recovery from neurological insults. Its utility in managing alcohol withdrawal symptoms further broadens its therapeutic scope. NINGBO INNO PHARMCHEM CO., LTD is committed to producing and supplying Mildronate that meets rigorous quality standards, ensuring its efficacy in these critical applications. The ongoing research into how to inhibit carnitine biosynthesis continues to uncover new facets of this important compound.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
