The ability to create precise molecular bonds is fundamental to countless scientific and industrial processes, from pharmaceutical synthesis to advanced materials science. N-Succinimidyl N-methylcarbamate, a chemical compound identified by its CAS number 18342-66-0, plays a crucial role in facilitating such controlled molecular interactions. Its unique reactivity profile makes it a favored reagent for chemists and researchers looking to achieve specific molecular linkages. As a leading supplier of this compound, we provide the tools for precision chemistry.
At its core, N-Succinimidyl N-methylcarbamate functions as a carbamoylating agent, specifically as a reactive equivalent of methyl isocyanate. Its structure features an N-hydroxysuccinimide (NHS) ester linked to a methylcarbamate group. The NHS ester is a well-known leaving group, particularly reactive towards primary amines. When N-Succinimidyl N-methylcarbamate encounters a molecule containing an amine group, the succinimide moiety is displaced, and a stable carbamate bond is formed between the amine and the methylcarbamoyl group. This reaction is highly efficient and typically proceeds under mild conditions, making it amenable to sensitive biomolecules and complex organic structures.
This specific reactivity makes N-Succinimidyl N-methylcarbamate invaluable in several key areas. In bioconjugation, it allows for the covalent attachment of functional groups to proteins, peptides, and antibodies via lysine residues or N-termini, which are rich in amine groups. This is critical for developing diagnostic assays, creating bioconjugates for targeted therapies, or immobilizing biomolecules onto surfaces. For researchers aiming to buy N-Succinimidyl N-methylcarbamate, understanding this mechanism ensures its effective application in their specific projects. Our role as a manufacturer and supplier is to provide the consistent quality necessary for these precise applications.
In pharmaceutical development, this reagent is instrumental in synthesizing intermediates and modifying drug molecules. The formation of carbamate bonds can alter a molecule's physicochemical properties, such as solubility and lipophilicity, which are critical for improving drug absorption and efficacy. For procurement professionals, sourcing high-purity N-Succinimidyl N-methylcarbamate from a reliable manufacturer in China ensures that these vital modifications can be performed with predictable outcomes. We offer competitive pricing for N-Succinimidyl N-methylcarbamate, supporting innovation in drug discovery.
The controlled chemistry of N-Succinimidyl N-methylcarbamate underscores its importance as a cornerstone reagent. Its ability to form stable carbamate bonds with amines under mild conditions makes it a preferred choice for researchers and manufacturers. We, as a dedicated N-Succinimidyl N-methylcarbamate supplier, are committed to providing this essential chemical with the highest standards of purity and reliability. Contact us to learn more about how N-Succinimidyl N-methylcarbamate can benefit your molecular bonding needs and to discuss bulk purchase options and pricing.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.