The ability to precisely link molecules together is a cornerstone of modern chemistry and biology. For tasks involving peptide synthesis and protein modification, few reagents are as universally employed and effective as 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, commonly known as EDC hydrochloride (CAS 25952-53-8). As a leading manufacturer and supplier in China, we understand the intricacies of this reagent and are dedicated to providing the highest quality product for your demanding applications.

At its core, EDC hydrochloride functions as a dehydrating agent, facilitating the formation of new covalent bonds by removing a molecule of water. In the context of peptide synthesis, this means enabling the formation of an amide bond between the carboxyl group of one amino acid and the amino group of another. This reaction proceeds via the formation of an O-acylisourea intermediate, which is highly reactive and susceptible to nucleophilic attack by an amine. The result is the elongation of a peptide chain, a fundamental step in creating complex proteins and therapeutic peptides.

Beyond basic peptide synthesis, EDC hydrochloride is a powerful tool for protein modification and bioconjugation. Its ability to activate carboxyl groups present on amino acid residues like aspartic acid and glutamic acid allows for the attachment of various molecules, including labels, drugs, or even other proteins. This is crucial for developing diagnostic assays, targeted drug delivery systems, and novel biomaterials. For researchers looking to buy EDC hydrochloride, its versatility in modifying proteins for specific functions is a major advantage.

A key feature that distinguishes EDC hydrochloride is its water solubility. This characteristic is vital for working with proteins and peptides, which often function and are best handled in aqueous environments. The ability to perform coupling reactions in water simplifies protocols, enhances the stability of biomolecules, and often leads to easier purification by removing water-soluble byproducts. When considering a supplier, understanding the purity (typically 99%) and the reliable water solubility of the EDC hydrochloride is essential for successful outcomes. We, as a China-based manufacturer, ensure these critical specifications are consistently met.

The price of EDC hydrochloride is a factor for many purchasing decisions. By engaging directly with manufacturers in China, researchers and companies can often access competitive pricing, especially for bulk quantities. We encourage those seeking to purchase this vital reagent to inquire about our pricing structures and the cost-effectiveness of our high-purity product. Our goal is to make this essential coupling agent accessible to fuel innovation in peptide and protein science.

In summary, 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is an indispensable reagent for anyone working with peptides and proteins. Its robust chemistry, combined with its water solubility, makes it an ideal coupling agent. As a committed supplier from China, we offer the quality and reliability you need to advance your research and development. We invite you to contact us for a quote and to learn more about how our EDC hydrochloride can benefit your work.