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The field of pain management has been significantly advanced by the development of synthetic opioid analgesics. At the heart of producing these powerful medications are precisely engineered chemical intermediates. trans-3-Methyl-4-phenylamino-1-phenylmethyl-4-piperidinecarbonitrile (CAS: 147292-25-9) is one such vital compound, serving as a critical precursor in the synthesis of fentanyl and its derivatives, which are cornerstones of modern pain relief strategies.
The chemical structure of this piperidine derivative is specifically designed to facilitate its role as a key intermediate in the complex synthesis pathways required for fentanyl citrate and fentanyl hydrochloride. These fentanyl formulations are indispensable for managing severe acute and chronic pain, particularly in surgical environments and for patients with debilitating conditions. The reliability and purity of this intermediate are paramount. NINGBO INNO PHARMCHEM CO.,LTD., a prominent manufacturer in China, specializes in producing this compound to exacting standards, often achieving purity levels of ≥98%. This commitment ensures that downstream pharmaceutical processes can proceed with confidence, leading to safe and effective medications.
Understanding the physical and chemical properties of trans-3-Methyl-4-phenylamino-1-phenylmethyl-4-piperidinecarbonitrile is essential for its effective use. As a white to pale yellow solid with a melting point between 114-117°C, it exhibits stability under typical storage and handling conditions. This stability is a crucial attribute for an intermediate that might undergo several transformations before yielding the final API. The expertise of companies like NINGBO INNO PHARMCHEM CO.,LTD. in chemical synthesis and quality control ensures that these properties are consistently met, providing a dependable supply for the pharmaceutical industry.
The contribution of Chinese chemical manufacturers to the global supply of pharmaceutical intermediates is substantial. NINGBO INNO PHARMCHEM CO.,LTD. stands out for its focus on high-value intermediates that are critical for advanced therapeutic applications. By providing high-purity trans-3-Methyl-4-phenylamino-1-phenylmethyl-4-piperidinecarbonitrile, they enable pharmaceutical companies to continue developing and manufacturing essential pain management treatments. The company's dedication to quality and innovation underscores the intricate relationship between chemical synthesis and modern healthcare solutions, highlighting the chemical foundations of effective pain management.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
