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Palmitoyl Chloride, identified by CAS number 112-67-4, is a fundamental chemical compound that serves as a crucial intermediate in various industrial synthesis processes. Characterized as a brown transparent liquid, its reactivity and specific chemical structure make it indispensable in sectors ranging from pharmaceuticals to the broader field of organic chemistry. For professionals seeking to buy Palmitoyl Chloride, understanding its synthesis and wide-ranging applications is essential for making informed procurement decisions.
Synthesis and Chemical Properties
Palmitoyl Chloride is synthesized typically through the reaction of palmitic acid with a chlorinating agent. Common methods involve using thionyl chloride (SOCl₂), oxalyl chloride ((COCl)₂), or phosphorus trichloride (PCl₃). These reactions convert the carboxylic acid group of palmitic acid into an acyl chloride, significantly increasing its reactivity. The resulting compound, Palmitoyl Chloride, possesses a 16-carbon chain, making it a long-chain fatty acyl chloride. This structure imbues it with specific solubility characteristics and reactivity patterns crucial for acylation reactions.
Its primary chemical characteristic is its high reactivity towards nucleophiles such as alcohols, amines, and water. This reactivity allows it to readily form esters, amides, and other derivatives. When seeking a Palmitoyl Chloride manufacturer, it’s important to confirm the purity, often specified as 98% or 99% assay, as this directly impacts the efficiency and outcome of subsequent synthesis steps.
Diverse Industrial Applications
The utility of Palmitoyl Chloride spans multiple industries. In the pharmaceutical sector, it is a key intermediate for preparing certain antibiotic formulations and other APIs that require lipophilic modifications for improved bioavailability or delivery. For example, its use in synthesizing chloramphenicol palmitate highlights its importance as an organic synthesis intermediate for antibiotics.
The cosmetic industry also heavily utilizes Palmitoyl Chloride as a precursor for synthesizing emollients, surfactants, and various skincare ingredients. Its ability to introduce a fatty acid chain can improve product texture, skin feel, and the stability of formulations. Beyond these, it finds application in the broader realm of specialty chemical synthesis, contributing to the production of polymers, lubricants, and other fine chemicals.
Sourcing Palmitoyl Chloride Reliably
For businesses relying on Palmitoyl Chloride, securing a dependable Palmitoyl Chloride supplier in China or globally is paramount. Factors to consider include product consistency, availability of technical documentation (like TDS and SDS), and competitive Palmitoyl Chloride price points. A thorough understanding of the material’s properties and applications ensures that procurement efforts are aligned with production goals, facilitating efficient and successful manufacturing outcomes.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
