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The Chemistry and Synthesis of Rasagiline Mesylate: A Pharmaceutical Perspective

The development of effective pharmaceuticals hinges on the precise synthesis and availability of high-quality chemical intermediates. Rasagiline Mesylate, known by its CAS number 136236-51-6, is a prime example of such a crucial intermediate, central to the treatment of Parkinson's disease. Understanding its chemical nature and manufacturing process is vital for pharmaceutical companies looking to source this compound reliably. NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-purity Rasagiline Mesylate for discerning pharmaceutical clients.

Rasagiline Mesylate is the mesylate salt of rasagiline, a molecule identified as (R)-N-propargyl-1-aminoindan. Chemically, it belongs to the propargylamine class and functions as a selective, irreversible inhibitor of monoamine oxidase B (MAO-B). The synthesis of rasagiline begins with the optical resolution of racemic N-benzyl-1-aminoindan using a chiral resolving agent, such as (R,R)-tartaric acid. This process isolates the pharmacologically superior R-enantiomer, which is then propargylated to yield rasagiline. The mesylate salt form is chosen for its favorable chemical stability, making it ideal for pharmaceutical formulation. When you consider where to buy Rasagiline Mesylate online, prioritize manufacturers who can demonstrate robust chiral purity.

The potency of Rasagiline Mesylate lies in its R-enantiomer, which exhibits significantly higher inhibitory activity against MAO-B compared to its S-enantiomer. This selectivity is critical for its therapeutic efficacy in Parkinson's disease, where increasing dopamine levels in the brain is the primary goal. By preventing the breakdown of dopamine, Rasagiline Mesylate helps to restore neurotransmitter balance and alleviate debilitating motor symptoms. As a premier Rasagiline supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying this highly pure R-enantiomer.

The pharmaceutical industry requires not only high purity but also a stable and dependable supply chain. For those needing to purchase (R)-N-2-Propynyl-1-indanamine, choosing a manufacturer with a proven track record is essential. NINGBO INNO PHARMCHEM CO.,LTD. understands the critical nature of this pharmaceutical intermediate. We ensure consistent quality and availability, allowing our clients to maintain their production schedules without interruption. Understanding the Rasagiline price for Parkinson's disease treatments also involves factoring in the reliability and quality offered by the supplier.

As a dedicated Rasagiline 136236-51-6 manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. employs advanced synthesis techniques and stringent quality control protocols. Our manufacturing processes are designed to meet the exacting standards of the pharmaceutical industry. We are equipped to handle bulk orders and provide comprehensive documentation to support regulatory submissions. Partnering with us ensures you have a reliable source of this vital chemical intermediate, enabling the consistent production of effective treatments for Parkinson's disease.

In conclusion, the chemical synthesis of Rasagiline Mesylate is a complex but vital process. Its specific structure and the enantiomeric purity are key to its function as a Parkinson's disease therapeutic. NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted manufacturer, providing the pharmaceutical sector with the high-quality Rasagiline Mesylate necessary for advancing patient care.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
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