NINGBO INNO PHARMCHEM CO.,LTD. proudly presents Chlorosulfonyl Isocyanate (CSI), a highly sought-after chemical compound identified by CAS NO: 1189-71-5. As a leading supplier in the chemical industry, we understand the critical role that high-quality raw materials play in various synthesis processes. CSI is an indispensable tool for researchers and manufacturers due to its exceptional reactivity and broad utility in organic chemistry.

Chlorosulfonyl Isocyanate, often abbreviated as CSI, holds the chemical formula CClNO3S and a molecular weight of 141.534. It typically appears as a clear liquid, sometimes described as colorless to light yellow. This versatile compound exhibits distinct physical properties that make it valuable for specialized applications. Its melting point is recorded at approximately -44 °C, while its boiling point stands around 107 °C at 760 mmHg. The density is noted as 1.8 ± 0.1 g/cm3. We ensure a minimum purity of 99% for our Chlorosulfonyl Isocyanate, meeting the stringent demands of modern chemical synthesis.

The remarkable versatility of Chlorosulfonyl Isocyanate stems from its unique molecular structure, which incorporates both chlorosulfonyl and isocyanate functional groups. These groups endow CSI with powerful electrophilic characteristics, featuring two reactive sites at the carbon and S(VI) centers. This dual reactivity enables CSI to participate in a wide array of chemical transformations, including addition, substitution, and condensation reactions. Its capacity for diverse reactions makes it an invaluable reagent for constructing complex organic molecules.

CSI's applications span several critical sectors. It is extensively utilized as a key pharmaceutical intermediate, playing a pivotal role in the synthesis of various active pharmaceutical ingredients. Notably, Chlorosulfonyl Isocyanate is instrumental in the preparation of beta-lactams, a class of antibiotics that are vital in modern medicine. Beyond pharmaceuticals, it finds significant use in the synthesis of agricultural chemicals and specialized polymers. Its reactivity also facilitates the cycloaddition to alkynes, the conversion of primary alcohols to carbamates, and the transformation of carboxylic acids and their chlorides into nitriles. Furthermore, CSI is employed in the preparation of N,N-disubstituted sulfamides and is a precursor to the well-known Burgess reagent, highlighting its diverse utility in complex chemical pathways.

Due to its high reactivity, Chlorosulfonyl Isocyanate requires careful handling. It is classified as toxic, corrosive, and reacts violently with water. Proper safety protocols, including the use of inert solvents such as chlorocarbons, acetonitrile, and ethers, are paramount during its synthesis and application. At NINGBO INNO PHARMCHEM CO.,LTD., we adhere to strict quality control measures and provide comprehensive safety data to ensure the safe and effective use of our products.

As a dedicated manufacturer and supplier of Chlorosulfonyl Isocyanate, NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering superior quality products that meet global standards. We maintain robust production capabilities and a consistent supply chain to fulfill the needs of our clients worldwide. When you are looking to buy or purchase this essential chemical, you can rely on our expertise and commitment to excellence. We understand the importance of competitive price without compromising on purity or reliability. Our goal is to be your trusted partner for high-grade chemical intermediates. For bulk inquiries or specific packaging requirements, our team is ready to assist you in securing your supply of Chlorosulfonyl Isocyanate.

Choose NINGBO INNO PHARMCHEM CO.,LTD. for your Chlorosulfonyl Isocyanate requirements and experience the difference that dedication to quality and customer satisfaction makes. We are here to support your innovations with reliable chemical solutions.