Ciclopirox Olamine, identified by its Chemical Abstracts Service (CAS) registry number 41621-49-2, represents a vital pharmaceutical raw material. It is the olamine salt form of ciclopirox, a distinguished synthetic broad-spectrum antifungal agent. This compound is widely recognized for its efficacy in treating various superficial mycoses, which are fungal infections affecting the skin, hair, and nails. Beyond its potent antifungal activity, Ciclopirox Olamine also exhibits beneficial antibacterial and anti-inflammatory properties, making it a multifaceted ingredient in dermatological formulations.

The mechanism of action of Ciclopirox Olamine is distinct from many other antifungal agents. Rather than primarily targeting specific enzymes in the fungal cell wall or membrane biosynthesis pathway, it operates by binding to and chelating essential trivalent cations, particularly iron (Fe3+) and aluminum (Al3+). These metal ions are critical co-factors for numerous enzymes involved in fungal cellular metabolism, respiration, and the synthesis of macromolecules like DNA and proteins. By sequestering these cations, Ciclopirox Olamine effectively inhibits the activity of these vital enzymes. This disruption leads to a cascade of cellular damage, including impaired energy production, altered cell membrane integrity, and disorganization of cell wall structure, ultimately resulting in fungal cell death. This unique mechanism contributes to a lower likelihood of resistance development compared to antifungals with more specific targets.

As a pharmaceutical raw material, Ciclopirox Olamine is typically supplied as a powder. This form is convenient for transportation, storage, and subsequent processing into various finished dosage forms such as creams, lotions, solutions, nail lacquers, and shampoos. The white appearance specified for high-quality material indicates purity and consistency, essential for pharmaceutical manufacturing processes. Key applications for Ciclopirox Olamine include the topical treatment of dermatophyte infections like tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch), commonly caused by species like *Trichophyton rubrum* and *Trichophyton mentagrophytes*. It is also highly effective against Tinea versicolor, a common fungal infection caused by *Malassezia* yeast.

The quality of Ciclopirox Olamine raw material is paramount to ensure the safety and efficacy of the final pharmaceutical products. Reputable suppliers adhere to stringent quality control measures, including detailed analysis specifications. Typical parameters evaluated include the assay percentage, which indicates the purity of the compound (often specified as ≥99%), loss on drying (LOD), ash content, and levels of heavy metals such as arsenic (As) and lead (Pb). Microbial limits, including total plate count and absence of specific pathogens like *E. Coli* and *Salmonella*, are also critically assessed to ensure the raw material is suitable for pharmaceutical use. Meeting recognized pharmacopoeial standards, such as the United States Pharmacopeia (USP), is a benchmark for quality and regulatory compliance globally.

Proper storage conditions are essential to maintain the stability and shelf life of Ciclopirox Olamine powder. It should be stored in a cool and dry place, away from strong light and heat, which can degrade the material. When stored correctly, the shelf life is typically specified as two years, ensuring the material retains its potency and quality for a significant period, facilitating efficient inventory management for pharmaceutical manufacturers. The packaging, often 25kg drums, is designed to protect the material from environmental factors during transport and storage.

For pharmaceutical companies developing and manufacturing topical antifungal treatments, sourcing high-quality Ciclopirox Olamine raw material is a critical decision. The consistency, purity, and compliance with international standards directly impact the quality and regulatory approval of their finished products. A reliable Ciclopirox Olamine manufacturer provides not only the material but also comprehensive documentation and technical support.

If you are looking to secure a consistent supply of premium Ciclopirox Olamine powder that meets USP standards, choosing an experienced and compliant Ciclopirox Olamine supplier is vital. We specialize in the production and supply of high-quality pharmaceutical raw materials, including Ciclopirox Olamine CAS 41621-49-2. Our manufacturing processes adhere to strict quality management systems, including GMP principles, ensuring the purity and reliability of our product. For companies needing to purchase Ciclopirox Olamine in various quantities, we offer competitive pricing and efficient logistics. We understand the importance of cost-effectiveness in pharmaceutical production and strive to provide an advantageous Ciclopirox Olamine price without compromising on quality.

Whether you are scaling up production or developing new formulations, partnering with a trusted supplier is key. Our commitment to quality extends beyond the product itself to providing excellent customer service and technical assistance. To buy Ciclopirox Olamine with confidence, reach out to discuss your specific requirements, obtain detailed specifications, and inquire about current pricing and availability. We are dedicated to being your reliable source for this essential antifungal raw material.