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Crisaborole Synthesis: The Essential Role of 4-(4-Bromo-3-formyl-phenoxy)-benzonitrile

The development of targeted and effective medications is a cornerstone of modern healthcare, and the journey from concept to patient often involves complex chemical synthesis. Crisaborole, a notable non-hormonal treatment for atopic dermatitis, exemplifies such innovation. Central to its production is the intermediate 4-(4-Bromo-3-formyl-phenoxy)-benzonitrile, identified by CAS number 906673-54-9. This compound is essential for creating the active pharmaceutical ingredient (API) that makes Crisaborole effective. NINGBO INNO PHARMCHEM CO.,LTD., a leading chemical manufacturer in China, is a premier supplier of this vital intermediate.

The synthesis of Crisaborole involves a series of precise chemical reactions where 4-(4-Bromo-3-formyl-phenoxy)-benzonitrile serves as a foundational building block. Its unique chemical structure, featuring specific functional groups, allows for the controlled introduction of other molecular components necessary for the final API. The high purity (≥98.0%) and consistent quality provided by NINGBO INNO PHARMCHEM CO.,LTD. are critical for ensuring the efficiency and yield of the synthesis process. As a result, sourcing this intermediate from a trusted manufacturer in China is a strategic advantage for pharmaceutical companies.

When you need to buy 4-(4-Bromo-3-formyl-phenoxy)-benzonitrile, choosing a supplier that guarantees quality and reliability is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is committed to excellence, leveraging advanced manufacturing techniques and stringent quality control protocols. Our role as a manufacturer in China enables us to offer competitive pricing and substantial production capacity, supporting both research-scale and commercial-scale projects. We understand the importance of a stable supply chain for pharmaceutical production, ensuring that our clients have continuous access to this essential intermediate.

The success of Crisaborole in the market is partly attributable to the quality of its precursors, making 4-(4-Bromo-3-formyl-phenoxy)-benzonitrile an indispensable component. NINGBO INNO PHARMCHEM CO.,LTD. takes pride in contributing to advancements in dermatological treatments by providing this high-grade pharmaceutical intermediate. Our dedication to meeting the stringent demands of the pharmaceutical sector solidifies our position as a key player in the global chemical supply network.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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