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The performance of solid oral dosage forms, such as tablets, is critically dependent on their ability to disintegrate effectively once ingested. This process is facilitated by disintegrants, and among the most effective is Crospovidone. NINGBO INNO PHARMCHEM CO.,LTD. highlights the importance of this excipient in modern drug formulation.
Crospovidone, also known as polyvinylpolypyrrolidone (PVPP), is a cross-linked polymer that functions as a superdisintegrant. Its primary mechanism of action involves rapid swelling and wicking upon contact with biological fluids. This process draws water into the tablet matrix, causing it to swell and break apart into smaller fragments, thereby accelerating the release of the active pharmaceutical ingredient (API). The crospovidone advantages in tablets include significantly reduced disintegration times, even at low concentrations (typically 2-5% w/w).
The efficiency of Crospovidone in promoting disintegration is often superior to that of other common disintegrants like starch or modified celluloses. Its performance is not significantly affected by pH, making it reliable across different physiological conditions. For those seeking to understand crospovidone PVPP granular for pharmaceuticals, its role in ensuring rapid and complete disintegration is a key benefit.
Furthermore, Crospovidone's unique properties also contribute to improving the solubility and dissolution rate of poorly soluble drugs. This is a crucial aspect in enhancing the bioavailability of many therapeutic agents. The crospovidone drug solubilization properties are highly valued by formulators aiming to optimize drug delivery.
NINGBO INNO PHARMCHEM CO.,LTD. is a trusted provider of high-quality Crospovidone. Companies looking to buy Crospovidone PVPP online can rely on NINGBO INNO PHARMCHEM CO.,LTD. for consistent quality and competitive pricing. By utilizing Crospovidone, pharmaceutical manufacturers can develop tablets that offer enhanced disintegration and improved drug release profiles.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
