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Decoding SDS-PAGE: The Critical Role of Sodium Dodecyl Sulfate in Protein Analysis

In the realm of biochemistry and molecular biology, Sodium Dodecyl Sulfate (SDS) is an indispensable reagent, most notably for its critical function in Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis, commonly known as SDS-PAGE. This technique is a fundamental tool for separating proteins based on their molecular weight.

NINGBO INNO PHARMCHEM CO.,LTD., as a reliable supplier of laboratory chemicals, provides high-purity SDS essential for the success of SDS-PAGE. The primary role of SDS in this process is protein denaturation. It disrupts the non-covalent bonds within protein molecules, causing them to unfold and lose their native three-dimensional structures.


Crucially, SDS also binds to proteins along their polypeptide chains, imparting a uniform negative charge to each molecule. This uniform charge-to-mass ratio ensures that when subjected to an electric field during electrophoresis, proteins migrate solely based on their size rather than their intrinsic charge or shape. This attribute makes SDS a vital component for accurate protein analysis.


The ability to buy SDS from a reputable manufacturer in China is essential for research institutions and laboratories. The quality and purity of the SDS directly impact the resolution and reliability of the experimental results. Understanding the chemical formulation and properties of SDS is key to its effective application in such sensitive analytical techniques.


For researchers and scientists, having a consistent and dependable source of SDS is paramount. Whether you are analyzing protein expression, studying protein interactions, or purifying proteins, the quality of your SDS matters. We, as a dedicated manufacturer, ensure our SDS meets the rigorous demands of modern laboratory practices. Considering the price and bulk availability can assist in optimizing laboratory budgets for essential reagents.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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