For chemists, researchers, and procurement specialists, specific CAS numbers act as vital identifiers for chemical compounds. CAS 229177-78-0 refers to 5,5',6,6',7,7',8,8'-Octahydro-1,1'-binaphthalene-2,2'-diamine, a molecule of significant interest in advanced organic synthesis and pharmaceutical development. This guide aims to demystify this compound, its characteristics, applications, and the practicalities of sourcing it.

Understanding CAS 229177-78-0: Octahydro-1,1'-binaphthalene-2,2'-diamine

At its core, this compound is a diamine derivative of the octahydro-1,1'-binaphthalene structure. The 'octahydro' prefix indicates that the naphthalene rings have been fully hydrogenated, resulting in saturated rings. The '1,1'-binaphthalene' signifies the linkage between the two fused ring systems, and the '2,2'-diamine' denotes the presence of two amine (-NH2) groups at the 2 and 2' positions. This specific arrangement confers crucial properties, including chirality and reactive amine functionalities.

Key characteristics often associated with this compound include:

• Purity: Typically supplied at high purities, often 97% or greater, essential for its use in sensitive chemical processes.
• Stereochemistry: The binaphthalene structure inherently leads to chirality, making it valuable for enantioselective applications.
• Reactivity: The amine groups are nucleophilic and can undergo a wide range of reactions, such as acylation, alkylation, and condensation.
• Storage Conditions: Often requires refrigerated storage (e.g., 0-6°C) to maintain its stability and purity.

Applications Driving Demand for CAS 229177-78-0

The utility of Octahydro-1,1'-binaphthalene-2,2'-diamine is broad, spanning several critical areas:

• Pharmaceutical Intermediates: It is a vital building block for synthesizing complex drug molecules where precise stereochemistry is required. Its incorporation can lead to APIs with enhanced efficacy and reduced side effects.
• Chiral Ligand Synthesis: Its chiral backbone makes it an ideal precursor for designing sophisticated chiral ligands used in asymmetric catalysis. These catalysts are indispensable for the production of single enantiomer pharmaceuticals.
• Material Science: Researchers are exploring its potential in creating novel materials, including porous frameworks like MOFs and COFs, and specialized polymers, for applications in catalysis, separation, and advanced sensing technologies.

Procurement: How to Buy Effectively

When you need to purchase CAS 229177-78-0, several factors should guide your procurement strategy:

• Identify Reputable Suppliers: Look for established chemical manufacturers and suppliers who specialize in fine chemicals and pharmaceutical intermediates.
• Verify Purity: Always request a Certificate of Analysis (CoA) to confirm the purity and other critical specifications.
• Consider Bulk vs. Research Quantities: Determine whether you need gram quantities for R&D or kilogram quantities for production and inquire about pricing accordingly.
• Explore Global Markets: Suppliers from regions like China often offer competitive pricing and a wide range of product availability. If you are looking to buy Octahydro-1,1'-binaphthalene-2,2'-diamine from China, work with manufacturers known for their quality control and export experience.

Understanding the significance of specific CAS numbers like 229177-78-0 is crucial for effective chemical procurement. By being informed about its properties and applications, R&D professionals and purchasing managers can confidently source this valuable intermediate to advance their projects.