Diethylstilbestrol, commonly known as DES, is a synthetic nonsteroidal estrogen with the chemical formula C18H20O2 and a molecular weight of 268.356. Appearing as a white powder, DES was historically one of the most widely prescribed pharmaceutical compounds in the mid-20th century, mirroring the pharmacological and therapeutic effects of natural estradiol. Its unique properties and potent biological activity made it a subject of extensive research and application for decades. As a bulk pharmaceutical intermediate, the quality and purity of Diethylstilbestrol powder are paramount, with assays typically demonstrating over 99% purity, rigorously confirmed through High-Performance Liquid Chromatography (HPLC) testing.

The chemical profile of Diethylstilbestrol is well-defined. It exhibits a melting point typically ranging from 169 to 175 degrees Celsius and a boiling point of approximately 407.1 degrees Celsius. Its density is around 1.107 g/cm³. These precise physical and chemical parameters are crucial for ensuring the integrity and consistency of the raw material, which is vital for any subsequent research or analytical application. NINGBO INNO PHARMCHEM CO.,LTD. adheres to stringent quality control measures, ensuring that every batch of Diethylstilbestrol powder meets or exceeds international standards such as USP, BP, and GMP guidelines, reflecting a deep commitment to excellence in pharmaceutical raw material supply.

Historically, Diethylstilbestrol was extensively used for various medical conditions. In human medicine, it was prescribed to prevent miscarriages, alleviate symptoms of menopause, treat atrophic vaginitis, female gonadal dysplasia, and even in certain cases of advanced breast and prostate cancers. Its utility in preventing postpartum lactation was also a notable application. In veterinary medicine, DES found applications as a growth promoter and for treating certain reproductive conditions. However, the legacy of Diethylstilbestrol is profoundly complex due to significant health concerns that emerged over time. In 1971, studies linked DES exposure in pregnant women to an increased risk of clear-cell adenocarcinoma, a rare vaginal cancer, in their daughters (known as "DES daughters"). This discovery led to a dramatic re-evaluation of its safety profile and a ban on its use for pregnancy-related issues.

Further scientific scrutiny cemented these concerns. On October 27, 2017, the International Agency for Research on Cancer (IARC) of the World Health Organization officially classified Diethylstilbestrol as a Group 1 carcinogen, meaning it is definitively carcinogenic to humans. This classification is based on sufficient evidence of carcinogenicity in humans. Following this, on December 27, 2019, Diethylstilbestrol was listed as a prohibited drug and compound for use in food animals. These regulatory actions underscore the critical importance of understanding and respecting the established risks associated with this compound. Consequently, its use in both human and veterinary medicine has been severely restricted or entirely discontinued in many parts of the world, emphasizing a global shift towards safer alternatives and more rigorous pharmaceutical oversight.

Despite its controversial past, Diethylstilbestrol retains significance in certain specialized fields. It continues to be utilized as a reference standard in analytical chemistry for validating testing methods and for pharmacokinetic studies where its unique properties make it valuable for understanding estrogenic pathways. Researchers also use it in controlled laboratory settings to investigate endocrine disruption, hormone-sensitive cancers, and to further elucidate the mechanisms of synthetic estrogens. NINGBO INNO PHARMCHEM CO.,LTD. understands the nuanced requirements for such sensitive compounds and offers Diethylstilbestrol powder exclusively for legitimate research, analytical, and highly controlled industrial applications, not for direct human or food animal consumption.

For those seeking a reliable Diethylstilbestrol manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. stands out through its commitment to quality and compliance. Our production facilities operate under strict ISO 9001 certification and follow robust HSE (Health, Safety, and Environment) protocols, ensuring both product purity and responsible manufacturing practices. We maintain a consistent production capacity, enabling us to serve global clients with efficiency. Our rigorous testing procedures, including comprehensive COA (Certificate of Analysis) for every batch, guarantee that our Diethylstilbestrol powder meets the highest standards for pharmaceutical-grade raw materials. When considering where to buy Diethylstilbestrol, prioritizing a supplier with transparent quality control and a strong ethical framework is crucial. We encourage prospective buyers to inquire about our product specifications and certifications.

As a leading Diethylstilbestrol supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to fostering long-term relationships with research institutions, pharmaceutical companies, and chemical distributors worldwide. We offer competitive Diethylstilbestrol price points, reflecting the quality and integrity of our product. For inquiries regarding bulk Diethylstilbestrol purchase or specific project requirements, our experienced team is readily available to provide detailed information and support. We ensure discreet and secure packaging, with transport packages negotiated to meet client-specific needs, facilitating global delivery. Our commitment extends beyond just supplying the product; it encompasses providing comprehensive support and ensuring that our customers receive material that empowers their critical research and development efforts, always within strict regulatory frameworks.