N,N-Dimethylformamide, commonly known as DMF, with CAS Registry Number 68-12-2, is a widely utilized organic compound playing a pivotal role across numerous industries. Produced by NINGBO INNO PHARMCHEM CO.,LTD., this clear, colorless, and hygroscopic liquid is distinguished by its exceptional solvency and low evaporation rate, making it an indispensable chemical for a diverse range of applications. Its molecular formula is C3H7NO, and it has a molecular weight of 73.09.
DMF exhibits a range of important physical and chemical properties that contribute to its broad utility. It possesses a density of approximately 0.945 g/mL at 20°C, a melting point of -61°C, and a boiling point of 153°C, alongside a flash point of 58°C. One of its most defining characteristics is its complete miscibility with water and a wide array of organic solvents, including alcohols, ethers, and aromatics. As a polar aprotic solvent, DMF is highly effective at dissolving both polar and non-polar substances, facilitating reactions that follow polar mechanisms, such as SN2 reactions. While pure N,N-Dimethylformamide is odorless, technical-grade or degraded samples may sometimes have a faint, distinctive odor, typically due to the presence of minor impurities like dimethylamine.
In the realm of chemical synthesis, DMF is an invaluable reaction solvent and sometimes a reagent. Its robust solvency allows it to dissolve a variety of organic compounds, making it ideal for numerous organic synthesis reactions. It is a common reagent in the Vilsmeier–Haack reaction, used for formylating aromatic compounds, and in the Bouveault aldehyde synthesis. Furthermore, DMF serves as a crucial solvent in Heck reactions and is frequently employed as a catalyst in the synthesis of acyl halides from carboxylic acids using agents like thionyl chloride. Its ability to stabilize reactive intermediates makes it a preferred choice for complex chemical processes, including the synthesis and purification of peptides and other small molecules in the pharmaceutical industry, where it acts as an exceptional reaction and crystallization solvent for active pharmaceutical ingredients (APIs).
The polymer and plastics industry heavily relies on DMF for its unique solvent properties. It is extensively used in the production of acrylic fibers, where its high solubility for polyacrylonitrile, combined with its miscibility with water, simplifies the manufacturing process. DMF is also the preferred solvent for spinning polyurethane-based elastomers and is vital for preparing polyurethane-based coatings for synthetic leather and various fabrics. Additionally, polymers such as polyvinylchloride, vinylchloride-vinylacetate copolymers, and certain polyamides readily dissolve in DMF. Its application extends to epoxy-based formulations and the manufacturing of semi-permeable membranes for critical applications like water treatment and dialysis, enabling the formation of fine and uniform layers.
Beyond synthesis and polymers, DMF finds diverse applications across various other sectors. In the petrochemical industry, it is utilized for the purification of acetylene from ethylene and butadiene from C4 streams, and for separating aromatics from aliphatic hydrocarbons. As an electrolyte solvent, its polarity and stability are leveraged in advanced technologies such as lithium-ion batteries and solar cells. It is also an effective solvent in the textile industry for synthetic fiber production, artificial leather manufacturing, and textile coating, ensuring durable and flexible finishes. Moreover, DMF acts as a powerful cleaning agent for industrial equipment, removing residues like resins, greases, oils, and polymers, and is a component in industrial paint strippers and solvent dyes. Its high solubility of inorganic substances also makes it valuable in the production of high voltage capacitors.
NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted manufacturer and supplier of high-quality Dimethyl Formamide (DMF). Committed to stringent quality control and efficient logistics, the company ensures that its DMF products meet the highest industry standards. With a focus on reliability and customer satisfaction, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive price options and streamlined processes for you to buy or purchase this essential chemical. The company prides itself on its capability for fast delivery, ensuring that your industrial operations maintain continuity and efficiency.
In conclusion, N,N-Dimethylformamide (DMF) is an exceptionally versatile and critical chemical compound whose unique properties make it indispensable across a spectrum of industrial applications. From facilitating complex organic syntheses and advanced polymer production to enabling innovations in pharmaceuticals and energy, DMF continues to be a cornerstone of modern chemical manufacturing. Partner with a reliable DMF supplier to secure your supply of this vital solvent.
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