Understanding the precise chemical properties of a compound is fundamental to unlocking its full potential in synthesis and material science. 1-Bromo-2-methoxynaphthalene, with the CAS number 3401-47-6, is a compound whose properties make it a valuable asset in organic chemistry. NINGBO INNO PHARMCHEM CO.,LTD., a prominent manufacturer and supplier based in China, offers this compound with detailed specifications to support diverse research and industrial applications.

The molecular formula of 1-Bromo-2-methoxynaphthalene is C11H9BrO, and its molecular weight is approximately 237.09 g/mol. Typically supplied with a purity of 97% or higher, this compound appears as a white to light yellow powder or crystal. Its physical state and appearance are crucial for handling and identification in laboratory settings. The melting point is reported in the range of 80-83 °C, providing a key parameter for quality assessment and process design.

The boiling point is noted as 319.2 ± 15.0 °C at 760 mmHg, indicating its relative stability at elevated temperatures, though proper handling under inert atmosphere might be advisable for prolonged storage or high-temperature reactions. The density is approximately 1.4 g/cm³, which is consistent with brominated aromatic compounds.

Chemically, the presence of the bromine atom on the naphthalene ring makes 1-Bromo-2-methoxynaphthalene a reactive aryl halide. This characteristic is central to its utility in various synthetic transformations, including palladium-catalyzed cross-coupling reactions like the Ullmann coupling, as previously discussed. These reactions are essential for forming new carbon-carbon bonds, which is a critical step in the synthesis of complex organic molecules. Furthermore, the methoxy group contributes to the electronic distribution within the molecule, potentially influencing its reactivity and selectivity in different chemical environments.

As an organic ligand for Covalent Organic Frameworks (COFs), its specific structural features are leveraged to build ordered porous materials. Its role as a precursor for catalysts, particularly in enantioselective aziridination, highlights its ability to be transformed into species that can precisely control the stereochemistry of reactions. This capability underscores the importance of its defined chemical properties for achieving high selectivity and yield.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers and chemists with reliable access to 1-Bromo-2-methoxynaphthalene, characterized by its defined chemical properties and high purity. By offering detailed specifications and consistent quality, we aim to facilitate the successful execution of advanced synthetic projects and the development of novel materials and pharmaceuticals.