L-Carnosine, scientifically known as beta-alanyl-L-histidine, is a naturally occurring dipeptide synthesized in the body from the amino acids beta-alanine and histidine. It is found in particularly high concentrations within muscle and brain tissues, highlighting its biological significance. First discovered by Russian chemist V.Gulevich, L-Carnosine has since been the subject of extensive research worldwide, revealing a range of intriguing biological activities.
At its core, L-Carnosine is recognized as a robust antioxidant. It possesses a remarkable capacity to scavenge various reactive oxygen species (ROS), including the highly destructive hydroxyl and peroxyl radicals, as well as superoxide and singlet oxygen. This broad-spectrum antioxidant activity is crucial in mitigating oxidative stress, a key contributor to cellular damage and aging processes. By neutralizing these harmful free radicals, L-Carnosine helps protect cellular components, including lipids, proteins, and DNA, from oxidative degradation.
Beyond its direct antioxidant effects, L-Carnosine is perhaps best known for its exceptional anti-carbonylation activity. Carbonylation is a non-enzymatic process where carbonyl groups attach to proteins, leading to protein damage, dysfunction, and the formation of advanced glycation end products (AGEs). This process is strongly implicated in age-related protein degradation and the pathogenesis of various chronic diseases. L-Carnosine is considered one of the most effective anti-carbonylation agents discovered to date. By reacting with carbonyl species, it effectively prevents protein carbonylation, thereby helping to maintain protein integrity and function. This protective mechanism is particularly relevant in preventing the cross-linking of skin collagen, a process that directly contributes to the loss of skin elasticity and the formation of wrinkles as we age. Therefore, L-Carnosine plays a vital role in supporting skin health and combating visible signs of aging.
Furthermore, research indicates that L-Carnosine acts as a regulator of crucial metal ions, specifically zinc and copper, in nerve cells. By chelating (binding to) these ionic metals, L-Carnosine can help prevent overstimulation of nerve cells that might otherwise occur due to excessive free metal concentrations. This chelation ability also contributes to its function in helping to remove excess or harmful metal ions from the body, acting as a natural detoxifying agent. This dual action – antioxidant and metal chelating – underscores L-Carnosine's multifaceted protective capabilities within biological systems.
The diverse functional properties of L-Carnosine make it a valuable ingredient across several industries, including cosmetics, food, and pharmaceuticals. In the cosmetic industry, its potent anti-aging effects, particularly its ability to protect collagen from glycation and oxidation, make it a sought-after component in skincare formulations aimed at reducing wrinkles, improving skin elasticity, and promoting a more youthful appearance. Its antioxidant properties also help protect the skin from environmental damage. As a raw material, L-Carnosine powder offers formulators a stable and versatile ingredient for incorporation into various product types, from creams and serums to supplements.
For use in pharmaceutical and food applications, the purity and quality of L-Carnosine powder are paramount. High-purity material, typically exceeding 98% or even 99%, is essential to ensure efficacy and safety. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing L-Carnosine powder meeting stringent quality standards, suitable for diverse high-grade applications. The powder form allows for flexible formulation and dosage. The stability of L-Carnosine powder under proper storage conditions (cool, dry area) ensures a reasonable shelf life, typically around 24 months, making it practical for manufacturing and supply chains.
Ongoing research continues to explore the full spectrum of L-Carnosine's benefits, including its potential roles in supporting athletic performance, cognitive function, and overall longevity. Its ability to buffer lactic acid in muscles, for instance, is an area of interest for sports nutrition. While many studies highlight its promising effects, particularly related to cellular protection and anti-glycation, the focus remains on leveraging its established properties in current applications while anticipating future developments.
For companies and researchers interested in harnessing the power of this exceptional dipeptide, sourcing high-quality L-Carnosine powder is the first step. Finding a reliable manufacturer and supplier capable of producing material with verified purity and consistency is crucial for successful product development. Information regarding the current market price, available grades (cosmetic, food, pharmaceutical), minimum order quantities, and detailed specifications can typically be obtained through direct inquiry. Understanding how to effectively buy or purchase this valuable ingredient, including available services like customization or sample requests, streamlines the procurement process. NINGBO INNO PHARMCHEM CO.,LTD. stands ready to support your needs for L-Carnosine powder.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
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