DL-4-Chlorophenylglycine, identified by its CAS number 6212-33-5, is a fascinating and industrially significant amino acid derivative. Its unique molecular structure, featuring a chiral center and a para-substituted chlorophenyl group, makes it a versatile building block in a wide array of chemical syntheses. As a leading manufacturer, understanding the in-depth role and properties of this compound is central to our commitment to providing high-quality intermediates. This article offers a comprehensive look at DL-4-Chlorophenylglycine, from its basic properties to its critical applications in modern chemistry.

Chemically, DL-4-Chlorophenylglycine is characterized as a white powder. Its molecular formula is C8H8ClNO2, with a molecular weight of approximately 185.61 g/mol. The presence of the chlorine atom on the phenyl ring influences its reactivity and the properties of compounds derived from it. The compound is a racemic mixture, meaning it contains equal amounts of both enantiomers. For many industrial applications, particularly in pharmaceuticals, the specific enantiomer may be required, necessitating further chiral resolution or asymmetric synthesis steps.

The primary utility of DL-4-Chlorophenylglycine lies in its role as a precursor and intermediate. Its amino and carboxylic acid functionalities, along with the aryl halide moiety, allow it to participate in a broad spectrum of organic reactions. Some key synthesis pathways include:

1. Peptide Synthesis: As an alpha-amino acid, it can be incorporated into peptides, leading to modified peptide structures with potentially altered biological activities or stability.

2. Pharmaceutical Synthesis: This is a major application area. DL-4-Chlorophenylglycine serves as a chiral building block for the synthesis of various pharmaceutical compounds, including antibiotics, antiviral agents, and other therapeutic molecules. The chlorophenyl group can be retained in the final drug structure or serve as a handle for further chemical modifications.

3. Agrochemicals: Its structure makes it suitable for incorporation into herbicides, insecticides, and fungicides, contributing to the development of advanced crop protection agents. The stability imparted by the aromatic ring and the potential for bioactivity are key advantages.

4. Dyestuffs: In some applications, it acts as an intermediate in the synthesis of specialized dyes, contributing to color chemistry.

The synthesis of DL-4-Chlorophenylglycine itself can be achieved through various routes, often starting from precursors like 4-chlorobenzaldehyde or related phenylacetic acid derivatives. As a manufacturer, we ensure that our production processes yield a high-purity product, typically exceeding 99.5% assay, with minimal impurities that could interfere with downstream reactions. We supply DL-4-Chlorophenylglycine in standard 25kg fiber drums, adhering to safe handling and transportation standards. For those seeking to buy DL-4-Chlorophenylglycine for their research or industrial needs, understanding its chemical versatility and our commitment to quality is paramount. We invite inquiries for quotes and further technical discussions.