20 YEARS OF PROFESSIONAL & DEDICATED SERVICE TO GLOBAL CUSTOMERS

Custom Manufacturing, Project Outsourcing, your Trusted Partner from China

Dl-4-Hydroxyphenylglycine (CAS 938-97-6): A Vital Intermediate in Antibiotics

In the intricate world of pharmaceutical manufacturing, the quality and purity of starting materials are paramount. Among the most critical of these foundational compounds is Dl-4-Hydroxyphenylglycine, a non-proteinogenic amino acid identified by its CAS No. 938-97-6. This off-white to pale yellow powder serves as an indispensable pharmaceutical intermediate, playing a pivotal role in the synthesis of some of the world's most widely used antibiotics. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to producing this vital compound at a purity level of over 99%, ensuring that pharmaceutical companies have access to a reliable and high-quality raw material for their life-saving medications.

Chemical Profile and Significance of Purity
Dl-4-Hydroxyphenylglycine, with the molecular formula C8H9NO3, possesses a unique chemical structure that makes it an ideal building block, or side chain, for a specific class of antibiotics. Its structure contains both a hydroxyl (-OH) group on the phenyl ring and a glycine moiety, which allows for specific chemical modifications during drug synthesis. The efficacy, safety, and stability of the final active pharmaceutical ingredient (API) are directly linked to the purity of this intermediate. Impurities can lead to unwanted side reactions, lower yields, and potentially harmful byproducts in the final drug product. Therefore, achieving a 99% purity degree, as verified through stringent quality control measures and certifications like ISO 9001, is not just a benchmark but a necessity in the pharmaceutical supply chain.

Core Application: The Backbone of Beta-Lactam Antibiotics
The primary and most significant application of Dl-4-Hydroxyphenylglycine is in the production of semi-synthetic beta-lactam (β-lactam) antibiotics. This class of drugs is one of the cornerstones of modern medicine, used to treat a vast array of bacterial infections. Dl-4-Hydroxyphenylglycine serves as the crucial side chain precursor for blockbuster antibiotics such as:

  • Amoxicillin: One of the most commonly prescribed antibiotics worldwide, used for respiratory infections, ear infections, skin infections, and more. The 4-hydroxyphenylglycyl side chain is essential for its broad spectrum of activity.
  • Cefadroxil: A first-generation cephalosporin antibiotic used to treat urinary tract infections, skin and soft tissue infections, and throat infections. Its structure and efficacy are directly derived from the incorporation of the hydroxyphenylglycine side chain.
  • Cephradine: Another versatile cephalosporin antibiotic whose synthesis relies on this key intermediate.
The presence of the 4-hydroxyphenyl group in these antibiotics enhances their ability to penetrate bacterial cell walls and inhibit the enzymes responsible for cell wall synthesis, leading to bacterial death. The global demand for these effective and trusted antibiotics directly fuels the market for high-purity Dl-4-Hydroxyphenylglycine.

Manufacturing Excellence and Quality Assurance
The synthesis of Dl-4-Hydroxyphenylglycine is a complex process that requires precise control over reaction conditions to achieve the desired high purity and to resolve the racemic mixture into its desired stereoisomers, as the D-form is often the biologically active precursor. At NINGBO INNO PHARMCHEM CO.,LTD., we employ advanced manufacturing technologies and a robust quality management system that adheres to international standards, including GMP and ISO 9001. Every batch of our Dl-4-Hydroxyphenylglycine powder is subjected to rigorous testing to confirm its identity, purity (>99%), and compliance with all specifications before it is released. This commitment to quality ensures that our clients receive a consistent and reliable product that meets the stringent requirements of the pharmaceutical industry.

As a dedicated manufacturer of specialty chemical ingredients, we understand the critical nature of our products. Our production capacity is scaled to meet global demand, ensuring a stable and dependable supply chain for our partners. For pharmaceutical developers and procurement managers, the ability to purchase Dl-4-Hydroxyphenylglycine from a trusted source is a critical step in their production pipeline.

Sourcing High-Quality Dl-4-Hydroxyphenylglycine
When sourcing a critical raw material like Dl-4-Hydroxyphenylglycine, it is imperative to partner with a reputable supplier who can guarantee quality, consistency, and a transparent supply chain. The market price of this intermediate can be influenced by raw material costs and global demand for antibiotics, but the ultimate value lies in the purity and reliability of the product. NINGBO INNO PHARMCHEM CO.,LTD. stands as a leading manufacturer and supplier, offering competitive price points without compromising on the exacting quality standards our clients depend on. For companies looking to buy top-grade Dl-4-Hydroxyphenylglycine, we provide a seamless procurement process, from inquiry to delivery, complete with comprehensive documentation and technical support. Making the decision to purchase from an established producer ensures product integrity and supply chain security, which are essential for uninterrupted pharmaceutical production. We invite you to contact us to discuss your specific requirements for Dl-4-Hydroxyphenylglycine and learn how we can become your trusted partner.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

Professional Export Experience

to Global Customers

WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
SEND US AN EMAIL

NAME*

EMAIL*

COMPANY

COUNTRY*

MESSAGE*

Previous: The Science of Youth: GHK-Cu Peptides for Advanced Skin Regeneration

Next: Harnessing Nature: The Power of High-Activity Bromelain Powder

All Rights Reserved