DL-alpha-Methylbenzylamine, identified by its CAS number 618-36-0, is a highly significant organic compound widely recognized as 1-Phenylethylamine or alpha-Methylbenzylamine. This primary amine is a colorless to light yellow liquid, characterized by its distinctive properties that make it indispensable across various industrial and scientific applications.

Possessing the molecular formula C8H11N and a molecular weight of 121.18 g/mol, DL-alpha-Methylbenzylamine exhibits a melting point around -65°C and a boiling point between 187-188°C. It has a density of approximately 0.94 g/mL at 25°C and a refractive index ranging from 1.5250 to 1.5270. Its flash point is notably at 69°C (175°F), highlighting the need for careful handling. While it shows limited solubility in water (about 4.2% at 20°C), it is readily miscible with common organic solvents such as alcohol and ether, making it highly versatile for various chemical reactions.

One of the most crucial aspects of DL-alpha-Methylbenzylamine is its utility as a chiral resolving agent and a chiral intermediate. Given its racemic nature (DL form), it is frequently employed in the optical resolution of other chiral compounds, often utilizing resolving agents like L-malic acid. This process allows for the separation and purification of enantiomers, which is critical in the pharmaceutical industry for producing highly specific and effective drug molecules.

Beyond its role in chiral chemistry, DL-alpha-Methylbenzylamine is a vital building block in organic synthesis. It can be prepared through methods like the reductive amination of acetophenone or the Leuckart reaction. It serves as a reactant for synthesizing various complex organic structures, including dihydro-5H-dibenz[c,e]azepinium salts. Its reactivity as a primary amine also makes it a valuable substrate for studying chemo-enzymatic kinetic resolution of other primary amines, contributing to advanced chemical research and development.

Furthermore, this compound finds application as an emulsifying agent due to its amphiphilic properties. In the realm of biochemical research, studies have also indicated its activity as a monoamine oxidase inhibitor (MAOI) and a semicarbazide-sensitive amine oxidase (SSAO) inhibitor, showcasing its diverse biochemical interactions.

Safety in handling DL-alpha-Methylbenzylamine is paramount. It is classified as corrosive, harmful if swallowed or in contact with skin, and causes severe skin burns and eye damage. Appropriate personal protective equipment, including protective gloves, clothing, and eye/face protection, must always be used. It should be stored under an inert atmosphere as it is stable but absorbs carbon dioxide from the air, and it is incompatible with strong oxidizing agents.

Supplied typically with high purity levels, often 98.5% minimum or 99% pure, DL-alpha-Methylbenzylamine is a cornerstone chemical for advanced manufacturing. For those seeking a reliable manufacturer and supplier of high-quality DL-alpha-Methylbenzylamine, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive price and consistent availability. To buy or purchase this essential chemical for your research or industrial needs, connect with experienced providers who can ensure product integrity and timely delivery.