Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
Rasagiline Mesylate, a selective MAO-B inhibitor widely used in Parkinson's disease management, requires careful consideration of potential drug interactions to ensure patient safety. Healthcare professionals and patients alike must be aware of the substances that can either enhance its effects dangerously or lead to adverse events.
One of the most critical areas of interaction involves other medications that affect serotonin levels. Concomitant use with antidepressants, such as SSRIs (Selective Serotonin Reuptake Inhibitors), SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors), tricyclic antidepressants, and others, can lead to serotonin syndrome, a potentially life-threatening condition. Symptoms include agitation, confusion, rapid heart rate, fever, and muscle rigidity. At least 14 days should typically elapse between discontinuing an antidepressant and starting Rasagiline Mesylate, and even longer for fluoxetine due to its long half-life.
Similarly, certain opioid pain relievers like meperidine, methadone, and tramadol, as well as cough suppressants like dextromethorphan, are contraindicated or require extreme caution when used with Rasagiline Mesylate due to the risk of serotonin syndrome or other severe reactions. Over-the-counter medications containing decongestants, like pseudoephedrine or phenylephrine, can also pose a risk, potentially leading to increased blood pressure.
Furthermore, the interaction with tyramine-rich foods is a significant concern. Tyramine, found in aged cheeses, cured meats, and certain fermented products, can cause a hypertensive crisis when consumed by patients taking MAO-B inhibitors. While Rasagiline Mesylate is more selective than older MAOIs, dietary precautions are still advised. For anyone looking to buy Rasagiline Mesylate or use it, consulting with a healthcare provider or pharmacist regarding all current medications and dietary habits is essential for safe and effective treatment.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
