20 YEARS OF PROFESSIONAL & DEDICATED SERVICE TO GLOBAL CUSTOMERS

Custom Manufacturing, Project Outsourcing, your Trusted Partner from China

DTT for DNA Synthesis: Ensuring Integrity and Efficiency

In the realm of molecular biology and biotechnology, the synthesis and manipulation of nucleic acids are fundamental. When working with thiolated DNA, a common challenge is the tendency for terminal sulfur atoms to dimerize, especially in the presence of oxygen. This dimerization significantly impedes the efficiency of critical coupling reaction experiments, such as the immobilization of DNA onto biosensor surfaces or the incorporation of modified nucleotides. To combat this, Dithiothreitol (DTT) emerges as an indispensable tool.

DTT functions as a potent reducing agent that effectively breaks these unwanted disulfide bridges formed between thiolated DNA molecules. By adding DTT to the DNA solution and subsequently removing it after a controlled reaction period, researchers can dramatically reduce dimerization. This restoration of free thiol groups ensures that the DNA remains in its active, monomeric form, ready for subsequent conjugation or hybridization processes. As a dedicated DTT manufacturer and supplier, we understand the precision required in these applications.

Our commitment as a DTT supplier in China is to provide materials of exceptional purity and consistency. When you buy DTT for your DNA synthesis needs, you can trust that you are receiving a product that meets rigorous quality standards, ensuring optimal performance and reproducible results. The DTT (CAS 3483-12-3) we offer is characterized by its high assay, typically above 98%, making it ideal for sensitive molecular biology workflows.

The strategic use of DTT not only enhances the success rate of DNA-based biotechnologies but also contributes to the cost-effectiveness of research and development. By preventing dimerization, it reduces the need for costly re-synthesis or purification steps. We encourage scientists and procurement managers to inquire about our DTT prices and bulk purchase options. Partner with a reliable DTT manufacturer to secure the integrity and efficiency of your thiolated DNA applications.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

Professional Export Experience

to Global Customers

WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
SEND US AN EMAIL

NAME*

EMAIL*

COMPANY

COUNTRY*

MESSAGE*

Previous: Optimizing Protein Purity: The Role of Dithiothreitol in Reduction

Next: Choosing a Dithiothreitol (DTT) Supplier: Purity, Price, and Performance

All Rights Reserved