Enduracidin Powder, also known as Enramycin, represents a significant advancement in animal health and nutrition. This powerful polypeptide antibiotic, originally derived from the soil bacterium Streptomyces fungicidus, has become an indispensable feed additive for promoting robust growth and maintaining intestinal well-being in livestock, particularly pigs and chickens. Its unique mode of action sets it apart, offering a reliable solution for producers seeking to optimize feed efficiency and minimize the impact of bacterial challenges.

At the heart of Enduracidin’s effectiveness is its potent activity against Gram-positive bacteria, a common cause of debilitating gut infections. Specifically, it demonstrates exceptional efficacy against pathogens like Clostridium perfringens, which is notorious for inducing necrotic enteritis in poultry and swine. The antibiotic operates by acting as an inhibitor of essential enzymes involved in bacterial cell wall biosynthesis, such as MurG. It primarily targets the transglycosylation step by binding with high affinity to Lipid II, a critical precursor in the peptidoglycan synthesis pathway. This disruption severely compromises bacterial cell wall integrity, leading to cell lysis and effective control of the pathogen population within the animal’s digestive tract.

The benefits of incorporating Enduracidin Powder into animal feed are multifaceted. Firstly, it significantly contributes to improved weight gain in both pigs and chickens. By suppressing harmful bacterial overgrowth, Enduracidin ensures that more nutrients from the feed are efficiently absorbed and utilized by the animal, rather than being diverted to support an unhealthy microbial balance. This leads directly to enhanced feed conversion rates, translating into better economic returns for producers. Furthermore, a key advantage of Enduracidin is its low propensity for developing drug resistance. Unlike some other antibiotics, Enduracidin modifies the bacterial population in the intestine in a way that makes it less likely for resistance to emerge, even after long-term use. This ensures its continued efficacy as a vital tool in animal production.

Safety is paramount in animal feed applications, and Enduracidin Powder excels in this regard. Studies have shown that after oral administration, Enduracidin primarily acts within the digestive tract and is minimally absorbed into the animal’s system. This rapid excretion ensures very low tissue residues, typically less than 25 μg/kg after a week of continuous use. Moreover, Enduracidin poses no toxic effect on crops, fish, or the broader environment once excreted by livestock, underscoring its profile as a safe and environmentally responsible animal-specific antibiotic.

As a leading manufacturer and supplier of high-quality pharmaceutical intermediates and feed additives, NINGBO INNO PHARMCHEM CO.,LTD. ensures that its Enduracidin Powder (CAS 11115-82-5) meets the most stringent quality standards, being suitable for food-grade feed additive applications. Our product is a fine white powder, boasting an assay of 99% minimum, ensuring consistent potency and performance. It has a robust shelf life of 24 months when stored properly in a cool, dry, dark location. For those looking to buy or purchase Enduracidin Powder, we offer a competitive price, backed by our commitment to excellence and prompt delivery. We encourage potential clients to connect with us to discuss their specific needs and explore how our premium Enduracidin Powder can benefit their operations.