In the intricate world of chemical synthesis, certain compounds stand out for their remarkable versatility and essential role in creating valuable end products. 1,3,5-Trimethoxybenzene, known scientifically as Phloroglucinol trimethyl ether and bearing the CAS number 621-23-8, is precisely such a compound. Its significance spans across the pharmaceutical industry as a crucial intermediate and extends into the broader domain of organic synthesis, making it a compound of considerable interest for procurement specialists and research scientists alike.
The primary application driving demand for 1,3,5-Trimethoxybenzene is its function as a pharmaceutical intermediate. The molecule’s structure, featuring three electron-donating methoxy groups on a benzene ring, renders it highly reactive in electrophilic aromatic substitution (EAS) reactions. This characteristic is invaluable for chemists aiming to construct complex molecular architectures, often serving as a key step in the synthesis of various drug candidates and bioactive molecules. For businesses looking to buy this chemical, securing a reliable supply of high-purity material (≥99%) is paramount to ensure consistent results in their synthesis processes. Partnering with established manufacturers in China can provide a cost-effective and dependable source.
Beyond its pharmaceutical roles, 1,3,5-Trimethoxybenzene is a staple reagent in general organic synthesis. It participates effectively in a range of reactions, including Friedel-Crafts acylation and alkylation, addition reactions, and various coupling chemistries. Its symmetrical substitution pattern also simplifies structural analysis, a significant advantage for R&D teams. For purchasing managers, identifying a supplier that offers competitive pricing for this chemical, especially for bulk orders, is a strategic move to optimize research and production costs. The availability of such intermediates is crucial for maintaining project momentum.
The consistent quality and predictable reactivity of 1,3,5-Trimethoxybenzene make it an attractive option for both academic research and industrial production. Its role as a precursor in creating triaryl- and triheteroarylmethanes, as well as its potential use in material science and dye chemistry, further highlights its broad utility. As a chemical supplier, we are dedicated to providing high-quality 1,3,5-Trimethoxybenzene to meet the diverse needs of our B2B clients. We encourage you to inquire about our product specifications, pricing, and procurement options, and to consider us your trusted partner for this vital chemical intermediate.
Manufacturing Facilities






Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.