For any chemical procured for industrial, pharmaceutical, or research applications, understanding its specifications and how quality is assured is fundamental. D-Glucuronic Acid Sodium Salt (CAS 14984-34-0) is no exception. As a supplier and manufacturer, we recognize that our clients, particularly R&D scientists and procurement managers, need confidence in the purity and consistency of the materials they buy. This article outlines the essential specifications and quality control measures for D-Glucuronic Acid Sodium Salt.

Key Specifications for D-Glucuronic Acid Sodium Salt

When evaluating D-Glucuronic Acid Sodium Salt, several key parameters define its quality and suitability for different applications. These are typically detailed in a Certificate of Analysis (CoA) provided by the manufacturer:

• Chemical Name and CAS Number: The definitive identifier is D-Glucuronic Acid Sodium Salt, CAS No. 14984-34-0.
• Molecular Formula and Weight: C6H11NaO7, with a molecular weight of approximately 218.14 g/mol (or 234.14 g/mol for the monohydrate).
• Appearance: Typically described as a white to off-white crystalline powder. Any deviation from this can indicate impurities or degradation.
• Assay (Purity): This is perhaps the most critical specification. For most research and pharmaceutical intermediate applications, an assay of ≥98% or ≥99% is required. This indicates the percentage of the target compound present.
• Moisture Content: As it can exist as a monohydrate, specifying the moisture content is important for accurate dosing and stability.
• pH: For solutions, the pH range (e.g., 6.0-8.0 for a 50g/l solution) can indicate the absence of acidic or alkaline impurities.
• Specific Rotation: This optical property is important for chiral compounds like D-Glucuronic Acid Sodium Salt, confirming its stereochemical integrity. Values like +21° are commonly cited.

Quality Control and Testing Methods

Manufacturers employ various analytical techniques to ensure that D-Glucuronic Acid Sodium Salt meets these stringent specifications. Common testing methods include:

• High-Performance Liquid Chromatography (HPLC): Used to determine the purity and identify/quantify any related impurities.
• Gas Chromatography (GC): May be used for specific impurity analysis, though HPLC is more common for this type of compound.
• Infrared (IR) Spectroscopy: Confirms the chemical structure and functional groups by matching the sample's spectrum to a reference standard.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Provides detailed structural information and can confirm the identity and purity of the compound.
• Titration: Used for assay determination or to measure specific functional groups.
• Karl Fischer Titration: Specifically used to determine the water content.

Partnering with a Quality Manufacturer

When you need to buy D-Glucuronic Acid Sodium Salt, choosing a supplier that prioritizes quality control is essential. Reputable manufacturers will readily provide a detailed CoA with each batch, confirming that the product has passed rigorous testing. They will also have robust internal quality management systems in place. For procurement managers, requesting samples and comparing CoAs from different potential suppliers is a wise approach to ensure you are sourcing the best possible material for your specific needs. Working with a trusted manufacturer in China can offer a balance of quality and competitive pricing.

In essence, a clear understanding of D-Glucuronic Acid Sodium Salt specifications and the quality assurance processes behind them empowers buyers to make informed decisions, ensuring the success of their research or manufacturing endeavors.