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For businesses operating in the chemical and pharmaceutical sectors, the quality of raw materials is not just a preference; it's a fundamental requirement that impacts product efficacy, safety, and regulatory compliance. 4-Hydroxyphenylacetic Acid (4-HPAA), a critical intermediate, exemplifies this principle. Ensuring you source high-purity 4-HPAA is paramount for successful synthesis and formulation.
Understanding the Specifications of 4-Hydroxyphenylacetic Acid
4-Hydroxyphenylacetic Acid (CAS: 156-38-7) is typically supplied as a white powder. The key specification that dictates its suitability for sensitive applications, particularly pharmaceutical synthesis, is its purity. Reputable manufacturers will offer 4-HPAA with a purity of ≥99%. Beyond assay purity, other important parameters include moisture content (Loss on Drying), residue on ignition, and melting point (typically 148-151°C). For R&D scientists and procurement managers, these specifications are critical benchmarks when evaluating potential suppliers.
The Importance of High Purity in Synthesis
In complex organic synthesis, even minor impurities can have significant downstream effects. For intermediates like 4-Hydroxyphenylacetic Acid used in the production of APIs such as Galantamine Hydrobromide or Olopatadine Hydrochloride, impurities can lead to:
Therefore, a commitment to purchasing ≥99% pure 4-HPAA is a strategic investment in the quality of your end product.
Finding Reliable Suppliers and Manufacturers
When looking to buy 4-Hydroxyphenylacetic Acid, diligence in supplier selection is key. Prioritize manufacturers who provide comprehensive Certificates of Analysis (COA) detailing purity and other relevant specifications. Companies that openly share their quality control processes and can demonstrate a consistent track record are ideal partners. Many leading chemical manufacturers based in China, including NINGBO INNO PHARMCHEM CO.,LTD., specialize in producing high-purity pharmaceutical intermediates and are well-equipped to meet global demand.
Making an Informed Purchase Decision
For procurement professionals, comparing offers based not just on price but also on quality assurance is crucial. Requesting samples for internal validation is a standard practice to confirm that the supplier's product meets your exact needs. Establishing a relationship with a dependable supplier ensures a stable supply chain, allowing your R&D and production teams to focus on innovation and manufacturing without concern for raw material quality.
By adhering to these quality-focused procurement principles, you can confidently source the high-purity 4-Hydroxyphenylacetic Acid necessary to drive your chemical and pharmaceutical projects forward.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
