For any R&D scientist or procurement manager involved in pharmaceutical manufacturing, understanding the detailed specifications of chemical intermediates is paramount. 4-(3-Methylphenyl)amino-3-pyridinesulfonamide (CAS 72811-73-5), a critical intermediate in the synthesis of Torasemide, is no exception. Ensuring that this compound meets stringent quality parameters directly impacts the efficacy, safety, and regulatory compliance of the final API.
The primary specification that buyers look for when they buy 4-(3-Methylphenyl)amino-3-pyridinesulfonamide is its purity. Reputable manufacturers and suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., will guarantee a minimum purity of ≥99.0%, often determined by HPLC analysis. This high level of purity is essential for minimizing unwanted side reactions during synthesis and ensuring the absence of problematic impurities in the final drug product.
Beyond overall purity, other key specifications are critical for a successful procurement. The appearance of the material is typically described as 'White to off-white crystalline powder'. This visual inspection is a quick yet important quality check. Deviations from this standard could indicate degradation or contamination. The price of the intermediate will, of course, be influenced by these specifications, with higher purity materials commanding a premium.
Detailed specifications for impurities are also vital. Typical limits include:
For procurement managers sourcing this intermediate, understanding these specifications is key to selecting a reliable manufacturer or supplier. Companies that clearly list these parameters and have robust quality control systems in place are more likely to provide consistent, high-quality material. When inquiring about availability and price, always ask for the detailed specification sheet and a recent COA.
Sourcing from experienced suppliers in China, like NINGBO INNO PHARMCHEM CO.,LTD., ensures that these critical specifications are met. Their expertise in producing pharmaceutical intermediates means a deep understanding of what is required for successful API synthesis. By focusing on these detailed specifications, procurement specialists can confidently purchase 4-(3-Methylphenyl)amino-3-pyridinesulfonamide, securing a vital component for their pharmaceutical manufacturing needs.
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