For professionals in pharmaceutical research and development, understanding the chemical synthesis and application of key intermediates is vital. This article focuses on 6-(Benzyloxy)-9-((1S,3R,3S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine (CAS 142217-80-9), a crucial intermediate in the synthesis of Entecavir. We aim to provide valuable insights for scientists looking to buy and procure this compound, highlighting its chemical significance and application context.

Entecavir is a potent antiviral drug used to treat Hepatitis B infections. Its synthesis involves complex organic chemistry, with CAS 142217-80-9 serving as a critical precursor. The molecular structure of this intermediate features a substituted purine ring linked to a modified cyclopentyl moiety, with multiple benzyloxy protecting groups. These structural elements are strategically incorporated to facilitate subsequent reactions, such as deprotection and functional group transformations, ultimately leading to the Entecavir API.

As a manufacturer specializing in advanced pharmaceutical intermediates, our expertise lies in mastering the complex synthesis routes required to produce compounds like CAS 142217-80-9. We employ rigorous reaction monitoring and purification techniques to ensure that the final product meets the stringent purity requirements for pharmaceutical applications. For researchers, understanding the synthetic pathway and the role of each functional group in this intermediate is key to optimizing their own processes or troubleshooting production challenges.

The primary application of this intermediate is in the production of Entecavir. However, its sophisticated chemical structure also makes it a valuable building block for other related research compounds or novel drug discovery programs. When considering the purchase of this chemical, it is essential to partner with suppliers who can provide detailed chemical information, including synthesis routes, analytical data (like NMR, HPLC, and Mass Spectrometry), and MSDS. As a reliable manufacturer in China, we make this information readily available to our clients.

For R&D scientists and procurement specialists, ensuring a reliable supply of high-quality intermediates is paramount to project success. We are committed to being a preferred supplier for CAS 142217-80-9, offering not just the chemical itself but also the technical support needed to integrate it effectively into your synthesis workflows. We invite you to learn more about our manufacturing capabilities and how we can support your critical research and development needs. Procuring this intermediate from a trusted source guarantees efficiency and quality in your drug synthesis endeavors.