3-Chloro-5-nitrobenzotrifluoride (CAS No. 401-93-4) stands as a pivotal chemical intermediate in the landscape of modern organic synthesis. This versatile compound, also known by its synonym 1-Chloro-3-nitro-5-(trifluoromethyl)benzene, is highly valued for its unique molecular structure, which incorporates a trifluoromethyl group, a nitro group, and a chlorine atom. These functional groups impart distinct chemical reactivity, making it an indispensable building block for the development of a wide array of sophisticated chemical compounds across various industries. Its strategic importance lies in its ability to facilitate complex reactions, enabling the creation of molecules with tailored properties.
Produced by NINGBO INNO PHARMCHEM CO.,LTD. with stringent quality controls, 3-Chloro-5-nitrobenzotrifluoride is characterized by its appearance as a colorless to light yellow transparent liquid, signifying its high purity and consistent quality. With an assay typically at ≥98.0%, this product guarantees reliability for sensitive applications. Its physical and chemical properties further underscore its utility: it has a density of approximately 1.5±0.1 g/cm3, a boiling point of 203.4±35.0 °C at 760 mmHg, and a flash point of 76.8±25.9 °C. These precise specifications ensure predictable performance in diverse synthetic pathways, allowing chemists to achieve desired reaction outcomes with high efficiency and yield.
The primary application of 3-Chloro-5-nitrobenzotrifluoride lies in its role as a crucial intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialized fine chemicals. The trifluoromethyl group often contributes to enhanced metabolic stability and lipophilicity in active pharmaceutical ingredients and pesticides, improving their efficacy and bioavailability. The nitro group can be readily reduced to an amino group, opening pathways for amide formation or other nitrogen-containing heterocycles. Furthermore, the strategically positioned chlorine atom offers a site for various nucleophilic substitution reactions or cross-coupling reactions, enabling the construction of intricate molecular architectures. For instance, it serves as a key precursor in the development of certain herbicides, fungicides, and pharmaceutical agents targeting specific biological pathways, contributing to advancements in medicine and agriculture. Its versatility makes it an invaluable asset for research and industrial production aiming for innovative chemical solutions.
As a reliable manufacturer and supplier of high-quality chemical products, NINGBO INNO PHARMCHEM CO.,LTD. ensures the consistent availability of 3-Chloro-5-nitrobenzotrifluoride. Our advanced production facilities and experienced team are dedicated to maintaining the highest standards of product purity and performance. We offer flexible packaging solutions, typically in 200 kg drums, with options to customize according to specific client requirements, ensuring safe and efficient delivery. For optimal preservation of product integrity, it is recommended to store 3-Chloro-5-nitrobenzotrifluoride in a cool, ventilated place, away from direct sunlight and incompatible materials. For detailed information regarding the current price of 3-Chloro-5-nitrobenzotrifluoride or to buy this essential chemical intermediate, please do not hesitate to contact NINGBO INNO PHARMCHEM CO.,LTD. We are committed to facilitating a smooth purchase process and providing excellent customer service globally.
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