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Estradiol Enanthate: A Look at its Chemical Structure and Pharmacological Significance

At NINGBO INNO PHARMCHEM CO.,LTD., we delve into the chemical intricacies of compounds that drive pharmaceutical innovation. Estradiol Enanthate, a prominent synthetic estrogen ester, is one such molecule. Understanding its chemical structure and its pharmacological implications is fundamental to appreciating its role in medicine.

Estradiol Enanthate is characterized by its molecular formula C25H36O3 and its CAS number 4956-37-0. Structurally, it is the enanthate (heptanoate) ester of estradiol. This esterification occurs at the 17β-hydroxyl group of estradiol. The addition of the long, lipophilic enanthate chain significantly alters the pharmacokinetic profile of estradiol. This modification is key to its function as a long-acting prodrug, enabling sustained release of active estradiol into the bloodstream after intramuscular administration.

The pharmacological significance of Estradiol Enanthate lies primarily in its ability to act as a depot for estradiol. Upon injection, the ester bond is gradually cleaved by esterases present in the body, releasing estradiol. This controlled release mechanism allows for lower peak plasma concentrations and a longer duration of action compared to administering free estradiol. This prolonged effect is crucial for applications like monthly injectable contraceptives and hormone replacement therapies, where maintaining stable physiological levels of estrogen is important.

The high purity of Estradiol Enanthate, often exceeding 99%, is a critical factor for its pharmaceutical applications. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to producing Estradiol Enanthate that meets rigorous quality standards, ensuring predictable pharmacological activity and minimizing potential side effects from impurities. The consistency in Estradiol Enanthate chemical properties directly impacts the efficacy and safety of the final drug products.

The practical implications of Estradiol Enanthate’s pharmacology are evident in its therapeutic uses. By providing a sustained delivery of estradiol, it contributes to effective management of menopausal symptoms and serves as a reliable component in birth control formulations. The reliability of Estradiol Enanthate suppliers such as NINGBO INNO PHARMCHEM CO.,LTD. ensures that this important pharmaceutical ingredient is available for these critical medical applications. We are committed to upholding the quality and availability of this vital compound.

In summary, the chemical structure of Estradiol Enanthate dictates its pharmacological behavior as a long-acting estrogen. Its development and application highlight the sophistication of modern pharmaceutical chemistry. NINGBO INNO PHARMCHEM CO.,LTD. continues to contribute to this field by providing high-quality Estradiol Enanthate, supporting advancements in healthcare.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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